Results 151 to 160 of about 1,080 (170)
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Veterinary and Comparative Oncology, 2023
AbstractThe most commonly utilized protocols to treat lymphoma in cats employ vincristine, cyclophosphamide and prednisone; with additional drugs sometimes used including L‐asparaginase and doxorubicin. Medical records were reviewed for 55 cats with alimentary lymphoma treated with a novel multiagent protocol using prednisolone, L‐asparaginase ...
Antony Stewart Moore +1 more
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AbstractThe most commonly utilized protocols to treat lymphoma in cats employ vincristine, cyclophosphamide and prednisone; with additional drugs sometimes used including L‐asparaginase and doxorubicin. Medical records were reviewed for 55 cats with alimentary lymphoma treated with a novel multiagent protocol using prednisolone, L‐asparaginase ...
Antony Stewart Moore +1 more
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Journal of Medicinal Chemistry, 2020
Klebsiella pneumoniae is one of the most critical opportunistic pathogens. TA systems are promising drug targets because they are related to the survival of bacterial pathogens. However, structural information on TA systems in K. pneumoniae remains lacking; therefore, it is necessary to explore this information for the development of antibacterial ...
Sung-Min Kang +4 more
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Klebsiella pneumoniae is one of the most critical opportunistic pathogens. TA systems are promising drug targets because they are related to the survival of bacterial pathogens. However, structural information on TA systems in K. pneumoniae remains lacking; therefore, it is necessary to explore this information for the development of antibacterial ...
Sung-Min Kang +4 more
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Molecular Microbiology, 2009
SummaryToxin–antitoxin loci have been identified in almost all free‐living prokaryotes, often in high copy numbers. The biological function and molecular targets of the abundant vapBC loci are not yet known. Here we analyse the vapBC loci of Salmonella LT2 and Shigella plasmid pMYSH6000.
Winther KS, Gerdes K
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SummaryToxin–antitoxin loci have been identified in almost all free‐living prokaryotes, often in high copy numbers. The biological function and molecular targets of the abundant vapBC loci are not yet known. Here we analyse the vapBC loci of Salmonella LT2 and Shigella plasmid pMYSH6000.
Winther KS, Gerdes K
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The FASEB Journal, 2020
VapC and VapB are the toxin and anti‐toxin proteins, respectively, of the VapCB toxin–antitoxin system found in bacteria and associated with stunting cell growth during stressful conditions. VapC homologs typically are tRNA endonucleases, and VapB homologs are known to bind to double‐stranded DNA, as well as VapC to inihibit its ...
Seth Patrick Jones +4 more
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VapC and VapB are the toxin and anti‐toxin proteins, respectively, of the VapCB toxin–antitoxin system found in bacteria and associated with stunting cell growth during stressful conditions. VapC homologs typically are tRNA endonucleases, and VapB homologs are known to bind to double‐stranded DNA, as well as VapC to inihibit its ...
Seth Patrick Jones +4 more
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VaPCE: Validation tool for postcoordinated SNOMED CT expressions (Preprint)
BACKGROUND The digitalization of healthcare has increased the demand for efficient data exchange, emphasizing semantic interoperability. SNOMED CT, a comprehensive terminology with over 360,000 medical concepts, supports this need. But it cannot cover all medical scenarios, particularly in complex cases.Tessa Ohlsen +2 more
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ABSTRACT The Mycobacteriophage D29 infects Mycobacterium species. Many of these are deadly human pathogens. In earlier studies, we performed proteomic analyses using a temperature-sensitive variant of D29, called D29ts12.
Rahul Shaw +4 more
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Rahul Shaw +4 more
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Ингибирование токсина VapC – способ предотвращения образования покоящихся форм микобактерий
Прикладная биохимия и микробиология, 2016openaire +1 more source
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2011
Ambrose Cheung, Niles Donegan
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Ambrose Cheung, Niles Donegan
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