Results 1 to 10 of about 26,624 (220)

Toxin–Antitoxin Systems in Bacillus subtilis [PDF]

open access: yesToxins, 2019
Toxin−antitoxin (TA) systems were originally discovered as plasmid maintenance systems in a multitude of free-living bacteria, but were afterwards found to also be widespread in bacterial chromosomes.
Sabine Brantl, Peter Müller
doaj   +3 more sources

Comparative genomic analysis of Acinetobacter spp. plasmids originating from clinical settings and environmental habitats [PDF]

open access: yes, 2018
Bacteria belonging to the genus Acinetobacter have become of clinical importance over the last decade due to the development of a multi-resistant phenotype and their ability to survive under multiple environmental conditions.
Pistorio, Mariano   +5 more
core   +2 more sources

Ser/Thr phosphorylation of Mycobacterium tuberculosis type II RelK toxin by PknK destabilizes TA interaction and interferes with toxin neutralization

open access: yesmBio
Toxin-antitoxin (TA) modules represent genetic elements implicated in bacterial persistence. Mycobacterium tuberculosis encodes 90+ TA modules, the majority of which are type II, comprising of a toxin component and an antitoxin counterpart that ...
Shafinaz Rahman Sarah   +6 more
doaj   +1 more source

Resonant activation: a strategy against bacterial persistence

open access: yes, 2010
A bacterial colony may develop a small number of cells genetically identical to, but phenotypically different from other normally growing bacteria. These so-called persister cells keep themselves in a dormant state and thus are insensitive to antibiotic ...
Hanggi P   +4 more
core   +1 more source

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification [PDF]

open access: yes, 2016
Filamentation induced by cyclic AMP (FIC)-domain enzymes catalyze adenylylation or other posttranslational modifications of target proteins to control their function.
Aragão, Hugo   +8 more
core   +1 more source

AAU-Specific RNA Cleavage Mediated by MazF Toxin Endoribonuclease Conserved in Nitrosomonas europaea

open access: yesToxins, 2016
Nitrosomonas europaea carries numerous toxin-antitoxin systems. However, despite the abundant representation in its chromosome, studies have not surveyed the underlying molecular functions in detail, and their biological roles remain enigmatic.
Tatsuki Miyamoto   +3 more
doaj   +1 more source

RHS-elements function as type II toxin-antitoxin modules that regulate intra-macrophage replication of Salmonella Typhimurium.

open access: yesPLoS Genetics, 2020
RHS elements are components of conserved toxin-delivery systems, wide-spread within the bacterial kingdom and some of the most positively selected genes known. However, very little is known about how Rhs toxins affect bacterial biology.
Magnus Stårsta   +8 more
doaj   +1 more source

Genomic Evolution of Two Acinetobacter baumannii Clinical Strains from ST-2 Clones Isolated in 2000 and 2010 (ST-2_clon_2000 and ST-2_clon_2010) [PDF]

open access: yes, 2016
Acinetobacter baumannii is a successful nosocomial pathogen due to its ability to persist in hospital environments by acquiring mobile elements such as transposons, plasmids, and phages. In this study, we compared two genomes of A.
Blasco, L.   +8 more
core  

A toxin-antitoxin module in Bacillus subtilis can both mitigate and amplify effects of lethal stress. [PDF]

open access: yesPLoS ONE, 2011
Bacterial type-2 (protein-protein) toxin-antitoxin (TA) modules are two-gene operons that are thought to participate in the response to stress. Previous work with Escherichia coli has led to a debate in which some investigators conclude that the modules ...
Xiangli Wu   +3 more
doaj   +1 more source

Toxin-antitoxin system [PDF]

open access: yes, 2018
Bakterije su razvile iznimnu sposobnost prilagodbe na različite životne uvjete. Uz pomoć raznih sustava i mehanizama daju brz stanični odgovor na stresore, tretman antibiotikom, stanje gladi i ostale nepovoljne uvjete. Jedan takav sustav pronađen je u
Matković, Katarina
core   +2 more sources

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