Results 31 to 40 of about 18,474 (175)

The Bacillus cereus spoIIS programmed cell death system

open access: yesFrontiers in Microbiology, 2015
Programmed cell death in bacteria is generally associated with two¬ component toxin antitoxin systems. The SpoIIS toxin-antitoxin system, consisting of a membrane bound SpoIISA toxin and a small, cytosolic antitoxin SpoIISB, was originally identified in ...
Jana eMelnicakova   +3 more
doaj   +1 more source

Molecular Characterization of SehB, a Type II Antitoxin of Salmonella enterica Serotype Typhimurium: Amino Acid Residues Involved in DNA-Binding, Homodimerization, Toxin Interaction, and Virulence

open access: yesFrontiers in Microbiology, 2020
Salmonella enterica serotype Typhimurium is a bacterium that causes gastroenteritis and diarrhea in humans. The genome of S. Typhimurium codes for diverse virulence factors, among which are the toxin-antitoxin (TA) systems.
Fernando Chimal-Cázares   +14 more
doaj   +1 more source

Expression, Purification, and Functional Analysis of Novel RelE Operon from X. nematophila

open access: yesThe Scientific World Journal, 2014
Bacterial toxin-antitoxin (TA) complexes induce programmed cell death and also function to relieve cell from stress by various response mechanisms. Escherichia coli RelB-RelE TA complex consists of a RelE toxin functionally counteracted by RelB antitoxin.
Jitendra Singh Rathore   +1 more
doaj   +1 more source

Diverse LXG toxin and antitoxin systems specifically mediate intraspecies competition in Bacillus subtilis biofilms.

open access: yesPLoS Genetics, 2021
Biofilms are multispecies communities, in which bacteria constantly compete with one another for resources and niches. Bacteria produce many antibiotics and toxins for competition.
Kazuo Kobayashi
doaj   +1 more source

sRNA Antitoxins: More than One Way to Repress a Toxin

open access: yesToxins, 2014
Bacterial toxin-antitoxin loci consist of two genes: one encodes a potentially toxic protein, and the second, an antitoxin to repress its function or expression. The antitoxin can either be an RNA or a protein.
Jia Wen, Elizabeth M. Fozo
doaj   +1 more source

Toxin-Antitoxin Systems of Staphylococcus aureus [PDF]

open access: yesToxins, 2016
Toxin-antitoxin (TA) systems are small genetic elements found in the majority of prokaryotes. They encode toxin proteins that interfere with vital cellular functions and are counteracted by antitoxins. Dependent on the chemical nature of the antitoxins (protein or RNA) and how they control the activity of the toxin, TA systems are currently divided ...
Christopher Schuster, Ralph Bertram
openaire   +4 more sources

The Haemophilus influenzae HipBA toxin–antitoxin system adopts an unusual three-component regulatory mechanism

open access: yesIUCrJ, 2022
Type II toxin–antitoxin (TA) systems encode two proteins: a toxin that inhibits cell growth and an antitoxin that neutralizes the toxin by direct intermolecular protein–protein interactions.
Ji Sung Koo   +4 more
doaj   +1 more source

Asking the 5 W's for designing next‐generation bioprocessing

open access: yesAIChE Journal, EarlyView.
Abstract Biotechnology is expanding beyond traditional, centralized fermentation and toward next‐generation bioprocessing paradigms that emphasize flexible deployment outside the laboratory with application‐specific performance. However, many bioprocesses fail to translate beyond proof‐of‐concept into industrially viable systems because early design ...
Sangdo Yook   +4 more
wiley   +1 more source

Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin

open access: yesmBio, 2023
A type II VapB14 antitoxin regulates biofilm dispersal in the archaeal thermoacidophile Sulfolobus acidocaldarius through traditional toxin neutralization but also through noncanonical transcriptional regulation.
April M. Lewis   +5 more
doaj   +1 more source

Vaginal host–microbe signatures linked to placental outcomes in mares

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule   +7 more
wiley   +1 more source

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