Results 51 to 60 of about 26,624 (220)

Molecular Characterization of SehB, a Type II Antitoxin of Salmonella enterica Serotype Typhimurium: Amino Acid Residues Involved in DNA-Binding, Homodimerization, Toxin Interaction, and Virulence

open access: yesFrontiers in Microbiology, 2020
Salmonella enterica serotype Typhimurium is a bacterium that causes gastroenteritis and diarrhea in humans. The genome of S. Typhimurium codes for diverse virulence factors, among which are the toxin-antitoxin (TA) systems.
Fernando Chimal-Cázares   +14 more
doaj   +1 more source

Shaping Pulses to Control Bistable Monotone Systems Using Koopman Operator [PDF]

open access: yes, 2016
In this paper, we further develop a recently proposed control method to switch a bistable system between its steady states using temporal pulses. The motivation for using pulses comes from biomedical and biological applications (e.g.
Goncalves, Jorge   +2 more
core   +2 more sources

The Bacillus cereus spoIIS programmed cell death system

open access: yesFrontiers in Microbiology, 2015
Programmed cell death in bacteria is generally associated with two¬ component toxin antitoxin systems. The SpoIIS toxin-antitoxin system, consisting of a membrane bound SpoIISA toxin and a small, cytosolic antitoxin SpoIISB, was originally identified in ...
Jana eMelnicakova   +3 more
doaj   +1 more source

Expression, Purification, and Functional Analysis of Novel RelE Operon from X. nematophila

open access: yesThe Scientific World Journal, 2014
Bacterial toxin-antitoxin (TA) complexes induce programmed cell death and also function to relieve cell from stress by various response mechanisms. Escherichia coli RelB-RelE TA complex consists of a RelE toxin functionally counteracted by RelB antitoxin.
Jitendra Singh Rathore   +1 more
doaj   +1 more source

TOXIN-ANTITOXIN REACTION WITHOUT NEUTRALIZATION [PDF]

open access: yesJournal of Experimental Medicine, 1932
1. Collodion particles adsorb diphtheria or tetanus or botulinus toxins. These toxins are retained on the particles when washed but are at least in part released in the animal. 2. The adsorbed toxins are neutralized by adsorption of the corresponding antitoxins but are unaffected by other serums. 3.
openaire   +2 more sources

sRNA Antitoxins: More than One Way to Repress a Toxin

open access: yesToxins, 2014
Bacterial toxin-antitoxin loci consist of two genes: one encodes a potentially toxic protein, and the second, an antitoxin to repress its function or expression. The antitoxin can either be an RNA or a protein.
Jia Wen, Elizabeth M. Fozo
doaj   +1 more source

Identification of a VapBC toxin–antitoxin system in a thermophilic bacterium Thermus thermophilus HB27 [PDF]

open access: yes, 2017
There are 12 putative toxin–antitoxin (TA) loci in the Thermus thermophilus HB27 genome, including four VapBC and three HicBA families. Expression of these seven putative toxin genes in Escherichia coli demonstrated that one putative VapC toxin TTC0125 ...
Fan Yuqi   +4 more
core   +2 more sources

Diverse LXG toxin and antitoxin systems specifically mediate intraspecies competition in Bacillus subtilis biofilms.

open access: yesPLoS Genetics, 2021
Biofilms are multispecies communities, in which bacteria constantly compete with one another for resources and niches. Bacteria produce many antibiotics and toxins for competition.
Kazuo Kobayashi
doaj   +1 more source

The Haemophilus influenzae HipBA toxin–antitoxin system adopts an unusual three-component regulatory mechanism

open access: yesIUCrJ, 2022
Type II toxin–antitoxin (TA) systems encode two proteins: a toxin that inhibits cell growth and an antitoxin that neutralizes the toxin by direct intermolecular protein–protein interactions.
Ji Sung Koo   +4 more
doaj   +1 more source

A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria

open access: yesNature Communications, 2022
Antimicrobial toxins are secreted by bacteria to kill rival species. Here the authors report the mechanism of inhibition of EsaD, a toxin secreted by some S.
Yongjin Wang   +17 more
doaj   +1 more source

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