Results 71 to 80 of about 18,474 (175)

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, Volume 13, Issue 37, 3 July 2026.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

A toxin-antitoxin module in Bacillus subtilis can both mitigate and amplify effects of lethal stress. [PDF]

PLoS ONE, 2011
Bacterial type-2 (protein-protein) toxin-antitoxin (TA) modules are two-gene operons that are thought to participate in the response to stress. Previous work with Escherichia coli has led to a debate in which some investigators conclude that the modules ...
Xiangli Wu, Xiuhong Wang, Karl Drlica, Xilin Zhao   +3 more
doaj   +1 more source

Decoding Viral Dark Matter: Metagenomic Prokaryotic Virus Characterization With Pharokka, Phold, and Phynteny

Current Protocols, Volume 6, Issue 7, July 2026.
Abstract Viral metagenomics is an increasingly powerful tool for understanding the function and structure of viruses across the diverse environments of our planet. However, decoding the functional potential of prokaryotic viral metagenomes is extremely challenging.
George Bouras, Susanna R. Grigson, Lindsay Durr, Bhavya Papudeshi, Vijini Mallawaarachchi, Sarah Vreugde, Robert A. Edwards   +6 more
wiley   +1 more source

The VapBC-4 Characterization Indicates It Is a Bona Fide Toxin-Antitoxin Module of Leptospira interrogans: Initial Evidence for a Role in Bacterial Adaptation

Microorganisms
Toxin-antitoxin (TA) systems are one of the bacterial adaptation mechanisms to adverse conditions. Leptospira interrogans serovar Copenhageni contains nine putative TA systems.
Bruna Oliveira Pigatto Azevedo, Deborah Kohn Damiano, Aline Florencio Teixeira, Ana Lucia Tabet Oller Nascimento, Luis Guilherme Virgilio Fernandes, Alexandre Paulo Yague Lopes   +5 more
doaj   +1 more source

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

Food Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun, Daoyan Xiao, Xingyue Li, Zhaofei Wang, Maoqin Xia, Chao Song, Hong‐Lei Li   +6 more
wiley   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 7, Page 1403-1426, July 2026.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Genetic Toolbox Expansion Enables Constitutively Fluorescent Lacticaseibacillus rhamnosus for Functional Microbiome Research

Microbial Biotechnology, Volume 19, Issue 7, July 2026.
We expanded the genetic toolkit for Lacticaseibacillus rhamnosus by enabling direct cloning, and leveraging five constitutive promoters and a repressor system. Fluorescent L. rhamnosus strains with different fluorochromes engineered with the high‐performing PtlpA promoter demonstrated functionality in microbial competition assays, supporting microbiome
Ilke Van Tente, Marc Blanch‐Asensio, Tom Eilers, Dieter Vandenheuvel, Sarah Lebeer, Shrikrishnan Sankaran, Irina Spacova   +6 more
wiley   +1 more source

Exploring the Potential of Zero‐Dimensional Carbon Nanomaterials in Photoluminescent, Electrochemiluminescent and Electrochemical Sensors

Advanced Materials Interfaces, Volume 13, Issue 11, 9 June 2026.
Zero‐dimensional carbon nanomaterials are presented as multifunctional platforms linking structure, property, and sensing performance. Surface engineering and heteroatom doping modulate electron‐transfer and luminescent behavior, enabling electrochemical, photoluminescent, and electrochemiluminescent detection. Fundamental design principles, analytical
Gustavo Martins, Jeferson Luiz Gogola, Ava Gevaerd, Cristiane Kalinke, Paulo Roberto de Oliveira, Fabio Roberto Caetano, Bruno Campos Janegitz, Márcio Fernando Bergamini, Luiz Humberto Marcolino‐Junior   +8 more
wiley   +1 more source

Solar–Chemical Hybrid‐Driven Phototroph for Biosynthesis

Rare Metals, Volume 45, Issue 8, August 2026.
Shuo Liu, Shilong Chen, Xijun Liu
wiley   +1 more source

On the Danysz Effect with reference to the Toxin-antitoxin Reaction [PDF]

Journal of Hygiene, 1907
Svante Arrhenius (1908) has taken exception to my criticism (1907) of his interpretation of the Danysz Effect with reference to the Toxin-Antitoxin reaction. In this paper he has given an interesting but rather far-fetched analogy to the Danysz Effect, which is, according to him, purely chemical in character and subject to the laws of chemical mass ...
openaire   +4 more sources