Results 81 to 90 of about 99,158 (152)
Crystallization of Doc and the Phd–Doc toxin–antitoxin complex [PDF]
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2008 The phd/doc addiction system is responsible for the stable inheritance of lysogenic bacteriophage P1 in its plasmidic form in Escherichia coli and is the archetype of a family of bacterial toxin-antitoxin modules. The His66Tyr mutant of Doc (Doc(H66Y)) was crystallized in space group P2(1), with unit-cell parameters a = 53.1, b = 198.0, c = 54.1 A ...
Garcia-Pino, Abel +5 more
openaire +5 more sources
MicroorganismsToxin-antitoxin (TA) systems are one of the bacterial adaptation mechanisms to adverse conditions. Leptospira interrogans serovar Copenhageni contains nine putative TA systems.
Bruna Oliveira Pigatto Azevedo +5 more
doaj +1 more source
conformational changes of antitoxin HigA by binding of toxin HigB
, 2021 학위논문(박사)--아주대학교 일반대학원 :분자과학기술학과,2021. 2General Introduction 1 Shigella flexneri 1 Persistent cells and toxin-antitoxin system 2 Multidrug resistance and multidrug tolerance 5 Six types of toxin-antitoxin system 7 Conditional cooperativity 10 Chapter
윤원수
core
, 2023 Bacterial toxin-antitoxin (TA) modules respond to various stressful conditions. The Gcn5-related N-acetyltransferase-type toxin (GNAT) protein encoded by the GNAT-RHH TA locus is involved in the antibiotic tolerance of Klebsiella pneumoniae.M215 ...
Tai, Cui +7 more
core +1 more source
Adverse Drug Reaction Study of Botulinum Toxin‐A in the Real World
Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.ABSTRACT Background Despite the increasing use of botulinum toxin type A (BoNT‐A) in aesthetic and therapeutic applications, its real‐world adverse drug reaction (ADR) profile remains incompletely characterized. Current evidence relies largely on small‐scale clinical observations rather than large, systematic analyses.
Jiaxu Gu +9 more
wiley +1 more source
Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes
, 2017 Toxin-antitoxin systems are widespread in the bacterial kingdom, including in pathogenic species, where they allow rapid adaptation to changing environmental conditions through selective inhibition of key cellular processes, such as DNA replication or ...
Brodersen, Ditlev E +3 more
core +1 more source
Turmeric and curcumin: From traditional medicine to modern therapeutic applications
JSFA reports, Volume 6, Issue 5, Page 160-178, May 2026.Abstract Turmeric (Curcuma longa), a medicinal plant, has maintained its cultural and therapeutic significance over centuries in Ayurveda, Unani, and Traditional Chinese Medicine. However, novel formulations and delivery methods are being developed to address these challenges.
Azma Nadeem +7 more
wiley +1 more source
The Biochemistry of VapBC Toxin-Antitoxins
, 2011 The VapBC toxin-antitoxin (TA) systems were first identified in 2005 and little is known about their contemporary biological function, despite the fact that VapBC TAs are the largest TA family and are widespread in bacteria and archaea (Arcus, Rainey ...
McKenzie, Joanna Leigh
core
Characterisation of VapBC Toxin-Antitoxins from Mycobacterium tuberculosis
, 2013 Toxin-antitoxin (TA) systems were identified more than 20 years ago on the mini F plasmid of Escherichia coli as plasmid stability elements; components responsible for purging bacterial cells that lack the plasmid from the population.
Sharrock, Abigail Victoria
core
Protein Science, Volume 35, Issue 5, May 2026.Abstract Pseudomonas aeruginosa is a prominent opportunistic pathogen whose virulence is closely linked to its Type III Secretion System (T3SS), a specialized apparatus that injects effector proteins into host cells. T3SS chaperones are essential for stabilizing, delivering, and regulating T3SS expression.
Jing Zhang
wiley +1 more source