Biopharmaceuticals for Cancer Treatment: An Update
Cancer Medicine, Volume 15, Issue 4, April 2026.ABSTRACT Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of ...
Anupom Deb Nath +6 more
wiley +1 more source
Insecticide@Silica Nanocontainers with High Cypermethrin Load and Improved Photostability
ChemNanoMat, Volume 12, Issue 4, April 2026.Cypermethrin@Octylsilicate core@shell nanocontainers (total diameter: 34 nm, diameter of cypermethrin core: 15 nm) exhibit high colloidal stability in water and high photochemical stability of the insecticide, allowing to reduce reapplication cycles and, thus, time and costs of insecticide application.
Mark Rutschmann +2 more
wiley +1 more source
mLife, Volume 5, Issue 2, Page 180-198, April 2026.Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei +9 more
wiley +1 more source
Caracterização da interação HipAB na Shewanella oneidensis MR1 [PDF]
, 2013 Mestrado em BioquímicaBacterial resistance is a major issue in research related to environmental and public health, due to the ineffectiveness of antibiotics, resulting from a subpopulation of bacterial cells entering a dormant state.
Henriques, Andreia Filipa Pereira
core
Geometric Properties of Isostables and Basins of Attraction of Monotone Systems [PDF]
, 2017 In this paper, we study geometric properties of basins of attraction of monotone systems. Our results are based on a combination of monotone systems theory and spectral operator theory.
Mauroy, Alexandre, Sootla, Aivar
core +3 more sources
An Optimal Control Formulation of Pulse-Based Control Using Koopman Operator [PDF]
, 2018 In many applications, and in systems/synthetic biology, in particular, it is desirable to compute control policies that force the trajectory of a bistable system from one equilibrium (the initial point) to another equilibrium (the target point), or in ...
Ernst, Damien +2 more
core +3 more sources
The HicA toxin from Burkholderia pseudomallei has a role in persister cell formation [PDF]
, 2014 © 2014 The Authors Journal compilation. ©2014 Biochemical Society.This is an open access article that is freely available in ORE or from the publisher's website.
Aaron Butt +62 more
core +1 more source
Replication and active partition of integrative and conjugative elements (ICEs) of the SXT/R391 family : the line between ICEs and conjugative plasmids is getting thinner [PDF]
, 2015 Integrative and Conjugative Elements (ICEs) of the SXT/R391 family disseminate multidrug resistance among pathogenic Gammaproteobacteria such as Vibrio cholerae.
A Bousquet +105 more
core +4 more sources
Regulating Toxin-Antitoxin Expression: Controlled Detonation of Intracellular Molecular Timebombs
Toxins, 2014 Genes for toxin-antitoxin (TA) complexes are widely disseminated in bacteria, including in pathogenic and antibiotic resistant species. The toxins are liberated from association with the cognate antitoxins by certain physiological triggers to impair ...
Finbarr Hayes, Barbara Kędzierska
doaj +1 more source
A competence-regulated toxin-antitoxin system in Haemophilus influenzae.
PLoS ONE, 2020 Natural competence allows bacteria to respond to environmental and nutritional cues by taking up free DNA from their surroundings, thus gaining both nutrients and genetic information.
Hailey Findlay Black +6 more
doaj +1 more source