Results 111 to 120 of about 26,624 (220)
Frontiers in MicrobiologyIntroductionThe stringent response is one of the fundamental mechanisms that control and modulate bacterial adaptation to stress conditions, such as nutrient limitation.
Monika Maciąg-Dorszyńska +3 more
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Infection and Drug Resistance, 2022 Made Rai Dwitya Wiradiputra,1,2 Piyatip Khuntayaporn,1,3 Krit Thirapanmethee,1,3 Mullika Traidej Chomnawang1,3 1Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 2Biopharmaceutical ...
Wiradiputra MRD +3 more
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PLoS Genetics, 2012 Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal population, can be mediated by toxin-antitoxin systems such as the Type III protein-RNA toxin-antitoxin
Tim R Blower +4 more
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TOXIN-ANTITOXIN IMMUNIZATION AGAINST DIPHTHERIA [PDF]
JAMA: The Journal of the American Medical Association, 1922 The development of antitoxin in the bodies of animals injected with diphtheria toxin is one of the best established of facts. Since von Behring and Roux announced the results of their investigations, large numbers of horses have been injected with toxin and have developed abundant antitoxin.
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Brazilian Journal of Medical and Biological Research, 2007 A method for the screening of tetanus and diphtheria antibodies in serum using anatoxin (inactivated toxin) instead of toxin was developed as an alternative to the in vivo toxin neutralization assay based on the toxin-binding inhibition test (TOBI test).
M.H. Sonobe +8 more
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Molecular bases and role of viruses in the human microbiome. [PDF]
, 2014 Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
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The role of efflux and physiological adaptation in biofilm tolerance and resistance
, 2016 Microbial biofilms demonstrate a decreased susceptibility to antimicrobial agents. Various mechanisms have been proposed to be involved in this recalcitrance. We focus on two of these factors.
Coenye, Tom, Van Acker, Heleen
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Toxin-Antitoxin Flocculation in Tetanus
Experimental Biology and Medicine, 1936 While the flocculation-test with diphtheria-toxin and antitoxin has given fairly good results,1, 2 the method has been found unreliable when applied to toxins and respective antitoxins of tetanus,3, 4, 5 botulinus,6, 7 staphylococcus,8 and Streptococcus scarlatinœ.9, 10Bronfenbrenner and Reichert6 found that antitoxin obtained by immunizing animals ...
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Druggability of bacterial toxins-antitoxins [PDF]
, 2015 53 p.-8 fig.-3 tab.Type II (proteic) toxin-antitoxin (TA) operons are widely spread in bacteria and archaea. They are organized as operons in which, usually, the antitoxin gene precedes the cognate toxin gene.
Balsa, Dolors +2 more
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Novel Single-Cell Method for Studying Toxin-Antitoxin Systems [PDF]
, 2016 细菌的抗药性危害日益严重，毒素－抗毒素（TA）系统在细菌内的异质性表达是多药耐受性存留细胞形成的重要原因。阐明致病菌中毒素－抗毒素系统的作用机理和生理功能对研发防控致病菌的新策略和疾病诊断治疗等具有重要意义。目前，对TA系统的研究主要集中在基因水平或转录水平，而传统基于蛋白质水平的检测方法，如WesternBlot等都是对大量细菌裂解液中的毒素抗毒素蛋白进行检测，是大量细菌内毒素抗毒素蛋白表现的集权平均。对单细菌水平的毒素－抗毒素蛋白进行快速逐一分析可揭示因集权平均而被掩盖的个体差异 ...
宋毅怡
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