Results 131 to 140 of about 19,351 (174)
A toxin-antitoxin system provides phage defense via DNA damage and repair. [PDF]
Nat CommunPu H +7 more
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Mechanisms of neutralization of toxSAS from toxin-antitoxin modules. [PDF]
Nat Chem BiolDominguez-Molina L +8 more
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A quinolone N-oxide antibiotic selectively targets Neisseria gonorrhoeae via its toxin-antitoxin system. [PDF]
Nat MicrobiolMix AK +12 more
europepmc +1 more source
The HicAB System: Characteristics and Biological Roles of an Underappreciated Toxin-Antitoxin System. [PDF]
Int J Mol SciEncina-Robles J +2 more
europepmc +1 more source
Mobile Genetic Elements, 2013 Toxin-antitoxin (TA) systems are small genetic elements composed of a toxin gene and its cognate antitoxin. The toxins of all known TA systems are proteins while the antitoxins are either proteins or non-coding RNAs. Based on the molecular nature of the antitoxin and its mode of interaction with the toxin the TA modules are currently grouped into five ...
Simon J Unterholzner +2 more
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Toxin–Antitoxin to the Rescue Against Phages
Nature Reviews Microbiology, 2022Ursula Hofer
exaly +3 more sources
Journal of the American Medical Association, 1926
Toxin-antitoxin mixture, as now made in accordance with the technic of Park1and his assistants, has proved itself remarkably free of the protein element from the clinical as well as the laboratory standpoint. A five year clinical study has proved satisfactorily the inability of toxin-antitoxin to sensitize individuals to horse protein; this conclusion ...
EDWARD L. BAUER, H. B. WILMER
openaire +1 more source
Toxin-antitoxin mixture, as now made in accordance with the technic of Park1and his assistants, has proved itself remarkably free of the protein element from the clinical as well as the laboratory standpoint. A five year clinical study has proved satisfactorily the inability of toxin-antitoxin to sensitize individuals to horse protein; this conclusion ...
EDWARD L. BAUER, H. B. WILMER
openaire +1 more source
Toxins-antitoxins: diversity, evolution and function
Critical Reviews in Biochemistry and Molecular Biology, 2011Genes for toxin-antitoxin (TA) complexes are widespread in prokaryote genomes, and species frequently possess tens of plasmid and chromosomal TA loci. The complexes are categorized into three types based on genetic organization and mode of action.
Hayes, Finbarr, Van Melderen, Laurence
openaire +3 more sources
Journal of the American Medical Association, 1927
In October, 1925, the health department of Kansas City, in conjunction and cooperation with the school board, undertook to inaugurate a campaign for the prevention of diphtheria. Having a good understanding of conditions in the past, particularly with respect to contagious diseases here, we estimated that if we could reach 20 per cent of the total ...
JOHN L. LAVAN, E. C. BLACK
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In October, 1925, the health department of Kansas City, in conjunction and cooperation with the school board, undertook to inaugurate a campaign for the prevention of diphtheria. Having a good understanding of conditions in the past, particularly with respect to contagious diseases here, we estimated that if we could reach 20 per cent of the total ...
JOHN L. LAVAN, E. C. BLACK
openaire +1 more source
Prokaryotic Toxin–Antitoxin Stress Response Loci
Nature Reviews Microbiology, 2005Although toxin-antitoxin gene cassettes were first found in plasmids, recent database mining has shown that these loci are abundant in free-living prokaryotes, including many pathogenic bacteria. For example, Mycobacterium tuberculosis has 38 chromosomal toxin-antitoxin loci, including 3 relBE and 9 mazEF loci. RelE and MazF are toxins that cleave mRNA
Anders Løbner-Olesen, Kenn Gerdes
exaly +4 more sources