Results 91 to 100 of about 26,624 (220)

T3SS effector and regulator discovery by predicting interacting partners of T3SS chaperones in Pseudomonas aeruginosa

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Pseudomonas aeruginosa is a prominent opportunistic pathogen whose virulence is closely linked to its Type III Secretion System (T3SS), a specialized apparatus that injects effector proteins into host cells. T3SS chaperones are essential for stabilizing, delivering, and regulating T3SS expression.
Jing Zhang
wiley   +1 more source

A Novel Small Molecule Accelerates Early Persister Regrowth and Potentiates Antibiotic Killing via MdtL–DcrB

open access: yesMicrobial Biotechnology, Volume 19, Issue 5, May 2026.
bymBDZ accelerates early regrowth of persister‐derived E. coli and potentiates antibiotic killing. Its activity requires the MdtL–DcrB axis and is associated with envelope‐linked transport changes that increase intracellular small‐molecule exposure during recovery, thereby enhancing clearance in early treatment windows. ABSTRACT Persister cells survive
Garin Park, Hyein Kim, Sooyeon Song
wiley   +1 more source

Bacterial type I toxin-antitoxin systems [PDF]

open access: yesRNA Biology, 2012
Toxin-antitoxin (TA) loci encode two-component systems that consist of a stable "toxin" whose ectopic overexpression either kills cells or confers growth stasis, and an unstable "antitoxin". TA systems have been initially discovered on plasmids, where they confer stability of maintenance through post-segregational killing (PSK). Plasmid loss results in
openaire   +2 more sources

Hepatitis B Virus, Pneumococcal, Diphtheria, and Tetanus Vaccination Responses in Compensated Cirrhosis

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims Cirrhosis favours infections that can lead to liver decompensation and death. Some of these infections can be prevented by vaccination. This study aimed to evaluate the immune response after HBV, pneumococcal, diphtheria, and tetanus vaccination in cirrhotic patients.
Vincent Haghnejad   +10 more
wiley   +1 more source

Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments

open access: yesWater and Environment Journal, Volume 40, Issue 2, Page 183-202, May 2026.
Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze   +3 more
wiley   +1 more source

Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains [PDF]

open access: yes, 2013
UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU.
Chang, Barbara J   +5 more
core   +3 more sources

Functional Analysis of the Role of Toxin-Antitoxin (TA) Loci in Bacterial Persistence. [PDF]

open access: yes, 2016
Bacterial Persistence: Methods and ProtocolsThe final publication is available at Springer via http://dx.doi.org/10.1007/978-1-4939-2854-5_11We have developed a method to analyze the functionality of putative TA loci by expressing them in Escherichia ...
Butt, Aaron T., Titball, Richard W.
core   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

Identification and characterisation of toxin-antitoxin systems (TA) in Burkholderia pseudomallei [PDF]

open access: yes, 2013
The aim of this study was to identify and characterise type II toxin-antitoxin (TA) systems in Burkholderia pseudomallei, the causative agent of the human disease melioidosis. 8 putative TA systems were identified within the genome of B. pseudomallei
Butt, Aaron Trevor
core  

Stabilization of the Virulence Plasmid pSLT of Salmonella Typhimurium by Three Maintenance Systems and Its Evaluation by Using a New Stability Test [PDF]

open access: yes, 2016
Certain Salmonella enterica serovars belonging to subspecies I carry low-copy-number virulence plasmids of variable size (50–90 kb). All of these plasmids share the spv operon, which is important for systemic infection.
Díaz-Orejas, Ramón   +4 more
core   +2 more sources

Home - About - Disclaimer - Privacy