Results 91 to 100 of about 99,158 (152)

On the Danysz Effect with reference to the Toxin-antitoxin Reaction [PDF]

open access: yesJournal of Hygiene, 1907
Svante Arrhenius (1908) has taken exception to my criticism (1907) of his interpretation of the Danysz Effect with reference to the Toxin-Antitoxin reaction. In this paper he has given an interesting but rather far-fetched analogy to the Danysz Effect, which is, according to him, purely chemical in character and subject to the laws of chemical mass ...
openaire   +4 more sources

A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS

open access: yes, 2012
International audienceAmong bacterial toxin-antitoxin systems, to date no antitoxin has been identified that functions by cleaving toxin mRNA. Here we show that YjdO (renamed GhoT) is a membrane lytic peptide that causes ghost cell formation (lysed cells
Wolfgang Peti   +25 more
core   +1 more source

Keeping the wolves at bay: antitoxins of prokaryotic type II toxin-antitoxin systems

open access: yesFrontiers in Molecular Biosciences, 2016
In their initial stages of discovery, prokaryotic toxin-antitoxin (TA) systems were confined to bacterial plasmids where they function to mediate the maintenance and stability of usually low- to medium-copy number plasmids through the post-segregational ...
Wai Ting eChan   +2 more
doaj   +1 more source

Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control

open access: yes, 2015
The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
core  

Toxin-antitoxin systems and its biotechnological applications

open access: yes, 2014
Toxin-antitoxin (TA) systems are important genetic modules composed by two elements: a toxin, that is always a protein, and an antitoxin, that can be a RNA or a protein and neutralizes the toxic effect of toxin.
Cangussu, Alex Sânder Rodrigues   +5 more
core   +1 more source

Toxin-Antitoxin Systems: A Key Role on Persister Formation in Salmonella enterica Serovar Typhimurium

open access: yesInfection and Drug Resistance, 2022
Made Rai Dwitya Wiradiputra,1,2 Piyatip Khuntayaporn,1,3 Krit Thirapanmethee,1,3 Mullika Traidej Chomnawang1,3 1Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 2Biopharmaceutical ...
Wiradiputra MRD   +3 more
doaj  

Regulating Toxin-Antitoxin Expression: Controlled Detonation of Intracellular Molecular Timebombs

open access: yesToxins, 2014
Genes for toxin-antitoxin (TA) complexes are widely disseminated in bacteria, including in pathogenic and antibiotic resistant species. The toxins are liberated from association with the cognate antitoxins by certain physiological triggers to impair ...
Finbarr Hayes, Barbara Kędzierska
doaj   +1 more source

Viral evasion of a bacterial suicide system by RNA-based molecular mimicry enables infectious altruism.

open access: yesPLoS Genetics, 2012
Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal population, can be mediated by toxin-antitoxin systems such as the Type III protein-RNA toxin-antitoxin
Tim R Blower   +4 more
doaj   +1 more source

A competence-regulated toxin-antitoxin system in Haemophilus influenzae.

open access: yesPLoS ONE, 2020
Natural competence allows bacteria to respond to environmental and nutritional cues by taking up free DNA from their surroundings, thus gaining both nutrients and genetic information.
Hailey Findlay Black   +6 more
doaj   +1 more source

The Biology and Biochemistry of PhoH2 proteins

open access: yes, 2013
PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
core  

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