Results 21 to 30 of about 16,660 (115)

Edward Jenner e a inoculação vacinal

open access: yesFilosofia e História da Biologia
Edward Jenner (1749-1823) figura como um dos nomes relacionados à inoculação vacinal. Ele realizou uma vacinação bem-sucedida. Em uma série de publicações, apresentou os procedimentos e resultados da vacinação tornando a imunização artificial conhecida ...
João Pedro Ocanha Krizek
doaj   +1 more source

D’ALEMBERT E A VARÍOLA* [PDF]

open access: yesKriterion
RESUMO A ordem assumida na construção da Encyclopédie de Diderot e D’Alembert supõe um modelo normativo epistêmico que não apenas condiciona a formação do cânone como horizonte de referencialidade, mas, simultaneamente, produz um modo de administração ...
Fabiano Lemos
doaj   +1 more source

Humanized immune system animal models and their recent applications

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 7, Page 1310-1324, July 2026.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli   +6 more
wiley   +1 more source

Building a Robust Investigator‐Initiated Platform: The I‐CARE Experience

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1537-1546, June 2026.
Investigator‐initiated studies that include information collected by patients are rising, but limited data is available on patient and investigator experience in this setting. The I‐CARE cohort included patients with inflammatory bowel disease (IBD) monthly collecting clinical information in 15 countries for up to 6 years.
Julien Kirchgesner   +906 more
wiley   +1 more source

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

open access: yesAdvanced Intelligent Systems, Volume 8, Issue 5, May 2026.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken   +4 more
wiley   +1 more source

Os trabalhadores com sinais de varíola no acervo da Delegacia Regional do Trabalho do Rio Grande do Sul, 1933-1944

open access: yesHistória, Ciências, Saúde: Manguinhos
Resumo A carteira profissional foi criada no Brasil em 1932. Em seguida, surgiram as Inspetorias Regionais do Trabalho, renomeadas, posteriormente, como Delegacias Regionais do Trabalho.
Aristeu Elisandro Machado Lopes
doaj   +1 more source

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

open access: yesChemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley   +4 more
wiley   +1 more source

Disease, religion and medicine: smallpox in nineteenth-century Benin Doenças, religião e medicina: a varíola no Benim, século XIX

open access: yesHistória, Ciências, Saúde: Manguinhos, 2012
The essay examines, with special reference to smallpox, the perception and interpretation of disease in pre-colonial Dahomey, present-day Republic of Benin. Because disease is seen primarily as a punishment from the gods and not just as a medical problem
Elisée Soumonni
doaj  

Use of the Aerosol Rabbitpox Virus Model for Evaluation of Anti-Poxvirus Agents

open access: yesViruses, 2010
Smallpox is an acute disease caused by infection with variola virus that has had historic effects on the human population due to its virulence and infectivity.
Thomas G. Voss, Chad J. Roy
doaj   +1 more source

Readiness Level of Spanish Labs to Detect Mpox Clade Ib: A Nationwide EQA

open access: yesJournal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT To assess the preparedness and diagnostic capacity of Spanish clinical microbiology laboratories to detect the emerging monkeypox virus (MPXV) Clade Ib through a nationwide external quality assessment. A blinded 16‐sample panel (serum and DNA eluates) containing MPXV Clade Ib, Clade II, vaccinia, and negatives was distributed.
Adolfo De Salazar   +49 more
wiley   +1 more source

Home - About - Disclaimer - Privacy