Results 31 to 40 of about 17,272 (115)

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

Advanced Intelligent Systems, Volume 8, Issue 5, May 2026.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken, Ahmed Choukri Abdullah, Olgac Ozarslan, Ziya Yıldız, Savas Tasoglu   +4 more
wiley   +1 more source

Use of the Aerosol Rabbitpox Virus Model for Evaluation of Anti-Poxvirus Agents

Viruses, 2010
Smallpox is an acute disease caused by infection with variola virus that has had historic effects on the human population due to its virulence and infectivity.
Thomas G. Voss, Chad J. Roy
doaj   +1 more source

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

Chemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley, Joshua D. Bryant, Samuel Vrana, Karuppiah Chockalingam, Zhilei Chen   +4 more
wiley   +1 more source

Readiness Level of Spanish Labs to Detect Mpox Clade Ib: A Nationwide EQA

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT To assess the preparedness and diagnostic capacity of Spanish clinical microbiology laboratories to detect the emerging monkeypox virus (MPXV) Clade Ib through a nationwide external quality assessment. A blinded 16‐sample panel (serum and DNA eluates) containing MPXV Clade Ib, Clade II, vaccinia, and negatives was distributed.
Adolfo De Salazar, Anabel Negredo, Juan Carlos Galán, Teresa Del Peso, Marta Illescas, Laura Martínez‐García, Concepción Gimeno, Federico García, María Paz Sánchez‐Seco, the QC Mpox Spain Collaborators, Sonia Algarate, Andrés Antón, Ana Milagro, Fernando Buñuel, Laura Calatayud, Pilar Catalán, Gregorio Marañón, Marta Domínguez‐Gil González, Manel Flores, Pablo Fraile, Ana Fuentes López, María del Carmen Garma, Mª Dolores Gómez‐Ruíz, Mónica Gozalo, Manuel Grau, Almudena Gutiérrez‐Arroyo, Silvia Hernáez, Águeda Hernández‐Rodríguez, Noelia Hernando, Flor Isabel Hidalgo, José Luis Juan, Eduardo Lagarejos, Miguel Julián Martínez‐Yoldi, Santiago Melón, Pablo Mendoza, Laura Merino, Milagrosa Montes, Jordi Niubó, María Dolores Ocete, Alejandra Pérez‐García, Jorge Alfredo Pérez‐García, Mercedes Pérez‐Ruiz, Sonia Pérez‐Castro, Jordi Reina, Romina Soledad Romero, Genoveva Santillana, Encarna Simarro, Mikel Urruticoechea, Laura Herrero, Francisca Molero   +49 more
wiley   +1 more source

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

mSphere, 2021
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson, Ashley V. Kondas, Mathew R. Mauldin, Jeffrey B. Doty, Irma M. Grossi, Clint N. Morgan, Sharon Dietz Ostergaard, Christine M. Hughes, Yoshinori Nakazawa, Chantal Kling, Brock E. Martin, James A. Ellison, Darin D. Carroll, Nadia F. Gallardo-Romero, Victoria A. Olson   +14 more
doaj   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.
ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Cameras or Divers? How Baited Remote Underwater Videos and ‘Long Swims’ Underwater Visual Census Complement Each Other on Coral Reefs

Ecology and Evolution, Volume 16, Issue 4, April 2026.
This study compares baited remote underwater videos (BRUV) and a rapid timed long swim (LS) UVC method to evaluate their ability in assessing relative abundance and diversity of large predatory reef fish from nine selected families. BRUVs were more effective in detecting mobile and bait‐attracted taxa such as Carangidae and recorded up to 28 unique ...
Kennedy Osuka‐Edeye, Melita Samoilys, Bryce D. Stewart, Colin J. McClean, Peter Musembi, Saleh Yahya   +5 more
wiley   +1 more source

Equilibrium energy spread and emittance in a Compton ring: An alternative approach

Physical Review Special Topics. Accelerators and Beams, 2014
In this article the Campbell’s theorem is used to evaluate the equilibrium emittance and energy spread in a Compton ring. This method allows us to have an efficient analytical approach separating the contributions of the Compton cross section from the ...
I. Chaikovska, A. Variola
doaj   +1 more source

Diagnóstico laboratorial da varíola: I. resultados do primeiro ano de atividade

Revista da Sociedade Brasileira de Medicina Tropical, 1970
Os autores escrevem a experiência obtida no Diagnóstico Laboratorial de Varíola, durante o primeiro ano de funcionamento de uma unidade montada para servir à Campanha de Erradicação de Varíola no Brasil.
H. G. Schatzmayr, J. A. Mesquita
doaj   +1 more source

Spherical Nucleic Acid Stabilized Cage Type Three‐Dimensional Electrochemiluminescence Probe for Sensitive and Amplification‐Free Diagnosis of Infectious Diseases

Exploration, Volume 6, Issue 2, April 2026.
This work developed a spherical nucleic acid stabilized cage‐type 3D electrochemiluminescence reporter probe for amplification‐free and ultrasensitive detection of pathogenic. Furthermore, a hand‐held detection device was designed, and we established a straightforward workflow enabling sample to answer within 15 min.
Yu Fu, Wenlu Song, Jinyan Lin, Wei Wang, Lunjing Liu, Wenjie Wu, Huiyi Yang, Jingru Wang, Yang Yang, Bowen Shu, Yideng Jiang, Yuhui Liao   +11 more
wiley   +1 more source