Results 51 to 60 of about 599,512 (246)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Continuous finite-time TSM control for electronic throttle system
The Journal of Engineering, 2019 This article examines the position tracking difficulties of the electronic throttle (ET) system and presents a continuous finite-time terminal sliding mode (TSM) control method.
Oluwatoyin Timothy Agbaje +3 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Extended state observer based fractional order sliding mode control for steer‐by‐wire systems
IET Control Theory & ApplicationsIn this paper, an extended state observer based fractional‐order sliding mode control strategy is studied for vehicle steer‐by‐wire systems (SBWSs). The parameter perturbation and external interference are considered in the dynamic model of SBWSs.
Quangang Shi +5 more
doaj +1 more source
The Journal of Engineering, 2019 To minimise the torque ripple for vector control of interior permanent magnet synchronous motor (IPMSM) of railway traction system, this study proposes a new velocity, torque and current three-loop control system, and designs a velocity and torque ...
Kaihui Zhao +6 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Machine learning–based robust trajectory tracking control for FSGR
The Journal of Engineering, 2019 Here, a robust adaptive trajectory tracking algorithm is proposed for free-form surface grinding robot (FSGR) in metal surface production line. Machine-learning method is used for robot dynamic approximation which is hard to obtain directly. Adaptive law
Lin Jia +5 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The Journal of Engineering, 2019 This study proposes a fault-tolerant matrix-converter-controlled IPMSM-drive system, in which a predictive speed-loop controller and a predictive current-loop controller are implemented to improve its dynamic responses, including transient responses and ...
Tian-Hua Liu, Shuo-Feng Chang
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source