Results 51 to 60 of about 8,447,173 (379)

Partitioning variance in reproductive success, within years and across lifetimes

open access: yesEcology and Evolution, 2023
Variance in reproductive success (sk2, with k = number of offspring) plays a large role in determining the rate of genetic drift and the scope within which selection acts. Various frameworks have been proposed to parse factors that contribute to sk2, but
Robin S. Waples
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Replication of linkage of familial hypobetalipoproteinemia to chromosome 3p in six kindreds

open access: yesJournal of Lipid Research, 2002
Familial hypobetalipoproteinemia (FHBL) is a genetically heterogeneous condition characterized by very low apolipoprotein B (apoB) concentrations in plasma and/or low levels of LDL-cholesterol (LDL-C) with a propensity to developing fatty liver.
Rosalind J. Neuman   +7 more
doaj   +1 more source

Fixed effects and variance components estimation in three‐level meta‐analysis

open access: yesResearch Synthesis Methods, 2011
Meta‐analytic methods have been widely applied to education, medicine, and the social sciences. Much of meta‐analytic data are hierarchically structured because effect size estimates are nested within studies, and in turn, studies can be nested within ...
S. Konstantopoulos
semanticscholar   +1 more source

Principal Flow Patterns across renewable electricity networks

open access: yes, 2018
Using Principal Component Analysis (PCA), the nodal injection and line flow patterns in a network model of a future highly renewable European electricity system are investigated. It is shown that the number of principal components needed to describe 95$\%
Brown, Tom   +5 more
core   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Dissecting total genetic variance into additive and dominance components of purebred and crossbred pig traits

open access: yesAnimal, 2019
The partition of the total genetic variance into its additive and non-additive components can differ from trait to trait, and between purebred and crossbred populations.
L. Tusell   +5 more
doaj   +1 more source

Combined Static and Motion Features for Deep-Networks Based Activity Recognition in Videos

open access: yes, 2018
Activity recognition in videos in a deep-learning setting---or otherwise---uses both static and pre-computed motion components. The method of combining the two components, whilst keeping the burden on the deep network less, still remains uninvestigated ...
Jayasundara, Vinoj   +5 more
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

PRINCIPAL COMPONENTS TO OVERCOME MULTICOLLINEARITY PROBLEM [PDF]

open access: yesOradea Journal of Business and Economics, 2019
The impact of ignoring collinearity among predictors is well documented in a statistical literature. An attempt has been made in this study to document application of Principal components as remedial solution to this problem.
Abubakari S.Gwelo
doaj  

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