Results 101 to 110 of about 1,347,601 (289)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Variational-Like Inclusions and Resolvent Equations Involving Infinite Family of Set-Valued Mappings

Fixed Point Theory and Applications, 2011
We study variational-like inclusions involving infinite family of set-valued mappings and their equivalence with resolvent equations. It is established that variational-like inclusions in real Banach spaces are equivalent to fixed point problems.
Ahmad Rais, Dilshad Mohd
doaj  

Parametric Extended General Mixed Variational Inequalities

Journal of Applied Mathematics, 2012
It is well known that the resolvent equations are equivalent to the extended general mixed variational inequalities. We use this alternative equivalent formulation to study the sensitivity of the extended general mixed variational inequalities without ...
Muhammad Aslam Noor
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Linearised higher variational equations

Discrete and Continuous Dynamical Systems, 2014
This work explores the tensor and combinatorial constructs underlying the linearised higher-order variational equations of a generic autonomous system along a particular solution. The main result of this paper is a compact yet explicit and computationally amenable form for said variational systems and their monodromy matrices.
openaire   +5 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

BIFURKATsIONNAYa USTOYChIVOST' SISTEMY «SOORUZhENIE - OSNOVANIE» NA BAZE MODELI VARIATsIONNOGO METODA V.Z. VLASOVA

Structural Mechanics of Engineering Constructions and Buildings, 2009
BIFURCATIONAL STABILITY OF THE STRUCTURE AND FOUNDATIONSYSTEM ON THE BASIS OF V.Z. VLASOV'S MODEL OF VARIATIONAL METHOD Inozemtzev V.K., Inozemtzeva O.V., Strelnikova K.A. A model joining the equations for a layer of the ground on the basis of
V K INOZEMTsEV, O V INOZEMTsEVA, K A STREL'NIKOVA   +2 more
doaj  

Strong nonlinear functional-differential variational inequalities: problems without initial conditions

Frontiers in Applied Mathematics and Statistics
Problems without initial conditions for evolution equations and variational inequalities appear in the modeling of different non-stationary processes within many fields of science, such as ecology, economics, physics, cybernetics, etc., if these ...
Mykola Bokalo, Iryna Skira, Taras Bokalo
doaj   +1 more source

Numerical Resolution of Fluid Dynamic Problems Using a Saddle Point Variational Formulation

Chemical Engineering Transactions, 2019
Variational methods are useful for finding numerical solutions of differential equations, which are the corresponding Euler-Lagrange equations to the stationary condition of the functional. Usually the functional is a maximum or a minimum with respect to
Reginaldo Guirardello
doaj   +1 more source