Results 81 to 90 of about 35,806,847 (310)

On the Variational Problems without Having Desired Variational Symmetries

open access: yesJournal of Mathematics, 2013
We will have an attempt to present a method for constructing variational problems without having a desired one-parameter transformation group as a variational symmetry.
Mehdi Nadjafikhah   +2 more
doaj   +1 more source

An Optimal Control Problem Governed by a Kirchhoff-Type Variational Inequality

open access: yesJournal of Applied Mathematics, 2020
This paper is concerned with an optimal control problem governed by a Kirchhoff-type variational inequality. The existence of multiplicity solutions for the Kirchhoff-type variational inequality is established by using some nonlinear analysis techniques ...
Chengfu Wang, Pengcheng Wu, Yuying Zhou
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Revised Variational Iteration Method for Solving Systems of Nonlinear Fractional-Order Differential Equations

open access: yesAbstract and Applied Analysis, 2013
A modification of the variational iteration method (VIM) for solving systems of nonlinear fractional-order differential equations is proposed. The fractional derivatives are described in the Caputo sense.
C. Ünlü, H. Jafari, D. Baleanu
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Novel Iterative Scheme and Its Application to Differential Equations

open access: yesThe Scientific World Journal, 2014
The purpose of this paper is to employ an alternative approach to reconstruct the standard variational iteration algorithm II proposed by He, including Lagrange multiplier, and to give a simpler formulation of Adomian decomposition and modified Adomian ...
Yasir Khan, F. Naeem, Zdeněk Šmarda
doaj   +1 more source

Ritz Variational Method for the Flexural Analysis of Rectangular Kirchhoff Plate on Winkler Foundation

open access: yesЖурнал інженерних наук, 2019
In this study, the Ritz variational method has been applied to solve the bending problem of rectangular Kirchhoff plate resting on Winkler foundation for the case of simply supported edges and transverse distributed load.
Ike C. C.
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

A Note on Doubly Nonlinear Parabolic Systems with Unilateral Constraint

open access: yes, 2011
We prove the existence and uniqueness of the solution to the doubly nonlinear parabolic systems with mixed boundary conditions. Due to the unilateral constraint the problem comes as a variational inequality.
Beneš, Michal
core   +1 more source

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