Results 91 to 100 of about 29,355 (249)
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Homoclinic solutions for a class of second-order Hamiltonian systems with locally defined potentials
Electronic Journal of Differential Equations, 2017 In this article, we establish sufficient conditions for the existence of homoclinic solutions for a class of second-order Hamiltonian systems $$ \ddot u(t)-L(t)u(t)+\nabla W\bigl(t,u(t)\bigr)=f(t), $$ where L(t) is a positive definite symmetric ...
Xiang Lv
doaj
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
A discontinuous problem involving the p-Laplacian operator and critical exponent in $mathbb{R}^N$
Electronic Journal of Differential Equations, 2003 Using convex analysis, we establish the existence of at least two nonnegative solutions for the quasilinear problem $$ -Delta_{p}u=H(u-a)u^{p^*-1} +lambda h(x)quadhbox{in }mathbb{R}^N $$ where $Delta_{p}u$ is the $p$-Laplacian operator, $H$ is the ...
Claudianor Oliveira Alves +1 more
doaj
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Existence of solutions to nonlocal elliptic equations with discontinuous terms
Electronic Journal of Differential Equations, 2012 In this article, we study the existence of nonnegative solutions for the elliptic partial differential equation $$displaylines{ -[M(|u|^{p}_{1,p})]^{1,p}Delta_{p}u = f(x,u) quadhbox{in } Omega , cr u = 0 quadhbox{on } partialOmega , }$$ where ...
Francisco Julio S. A. Correa +1 more
doaj
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Electronic Journal of Differential Equations, 2015 In this article we study the existence and concentration behavior of bound states for a nonlinear Schrodinger-Poisson system with a parameter $\varepsilon>0$.
Patricia L. Cunha
doaj
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source