Results 71 to 80 of about 992,040 (338)

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

THE METHOD OF SYSTEMATIC VARIATIONS

open access: yesSoil Science, 1963
info:eu-repo/semantics ...
openaire   +3 more sources

Adaptive thresholding by variational method [PDF]

open access: yesIEEE Transactions on Image Processing, 1998
When using thresholding method to segment an image, a fixed threshold is not suitable if the background is uneven. Here, we propose a new adaptive thresholding method using variational theory. The method requires only one parameter to be selected and the adaptive threshold surface can be found automatically from the original image.
Chan, FHY, Lam, FK, Zhu, H
openaire   +5 more sources

Variational approach to transport in quantum dots

open access: yes, 2011
We have derived a variational principle that defines the nonequilibrium steady-state transport across a correlated impurity mimicking, e.g., a quantum dot coupled to biased leads.
A. C. Hewson   +2 more
core   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Mode Variational LSTM Robust to Unseen Modes of Variation: Application to Facial Expression Recognition [PDF]

open access: yesarXiv, 2018
Spatio-temporal feature encoding is essential for encoding the dynamics in video sequences. Recurrent neural networks, particularly long short-term memory (LSTM) units, have been popular as an efficient tool for encoding spatio-temporal features in sequences.
arxiv  

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Infinitely many solutions for a Hénon-type system in hyperbolic space

open access: yesAdvances in Difference Equations, 2020
This paper is devoted to studying the semilinear elliptic system of Hénon type {−ΔBNu=K(d(x))Qu(u,v),−ΔBNv=K(d(x))Qv(u,v),u,v∈Hr1(BN),N≥3, $$ \textstyle\begin{cases} -\Delta _{\mathbb{B}^{N}}u= K(d(x))Q_{u}(u,v), \\ -\Delta _{\mathbb{B}^{N}}v= K(d(x))Q_ ...
Patrícia Leal da Cunha   +1 more
doaj   +1 more source

Some reflections on variational methods for partial differential inclusions [PDF]

open access: yesarXiv, 2016
We discuss the application of variational methods, based on non-smooth critical point theory, to a general class of partial differential inclusions.
arxiv  

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