Results 71 to 80 of about 31,755,712 (367)

Self-Adaptive Implicit Methods for Monotone Variant Variational Inequalities

Journal of Inequalities and Applications, 2009
The efficiency of the implicit method proposed by He (1999) depends on the parameter heavily; while it varies for individual problem, that is, different problem has different "suitable" parameter, which is difficult to find.
Ge Zhili, Han Deren
doaj   +2 more sources

Implicit particle methods and their connection with variational data assimilation

, 2012
The implicit particle filter is a sequential Monte Carlo method for data assimilation that guides the particles to the high-probability regions via a sequence of steps that includes minimizations.
Alexandre J. Chorin, Arulampalam, Bennet, Bickel, Buehner, Cappé, Carpenter, Chorin, Chorin, Chorin, Chorin, Chorin, Conn, Cornebise, Courtier, Courtier, Dimet, Doucet, Doucet, Ethan Atkins, Evensen, Evensen, Evensen, Fedorenko, Fertig, Fletcher, Fournier, Geweke, Goodman, Gordon, Hammersley, Hunt, Johansen, Kalman, Kalman, Kalnay, Kalnay, Kalos, Kass, Kass, Kloeden, Kurapov, Liu, Liu, Liu, Liu, Lorenz, Matthias Morzfeld, Miller, Moral, Morzfeld, Morzfeld, Nocedal, Pitt, Rabier, Smith, Smídl, Snyder, Talagrand, Talagrand, Tremolet, van Leeuwen, van Leeuwen, Zupanski   +63 more
core   +3 more sources

Variational log‐ Gaussian point‐process methods for grid cells [PDF]

, 2023
Michael E. Rule, Prannoy Chaudhuri‐Vayalambrone, Marino Krstulović, Marius Bauža, Julija Krupic, Timothy O’Leary   +5 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

About existence and regularity of positive solutions for a quasilinear Schrödinger equation with singular nonlinearity

Electronic Journal of Qualitative Theory of Differential Equations, 2020
We establish the existence of positive solutions for the singular quasilinear Schrödinger equation \begin{equation*} \begin{cases} -\Delta u -\Delta (u^{2})u=h(x) u^{-\gamma} + f(x,u)& \mbox{in } \Omega,\\ u(x)=0&\mbox{on }\partial \Omega, \end{cases ...
Ricardo Alves, Mariana Reis
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Variational Methods for Nuclear Systems with Dynamical Mesons

, 1993
We derive a model Hamiltonian whose ground state expectation value of any two-body operator coincides with that obtained with the Jastrow correlated wave function of the many-body Fermi system.
Alberico, Benhar, Blaizot, Cenni, Clark, Fantoni, Fantoni, Fantoni, Feynman, Gari, Pandharipande, R. Cenni, Riska, Rosati, S. Fantoni, Schulz   +15 more
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Variational Methods in AdS/CFT

, 2009
We prove that the AdS/CFT calculation of 1-point functions can be drastically simplified by using variational arguments. We give a simple universal proof, valid for any theory that can be derived from a Lagrangian, that the large radius divergencies in 1-
E. Witten, Francisco Rojas, J. Maldacena, M. Bianchi, Máximo Bañados, Tomás Andrade   +5 more
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source