Results 61 to 70 of about 165,487 (274)
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Jacobi equations using a variational principle
A variational principle is proposed for obtaining the Jacobi equations in systems admitting a Lagrangian description. The variational principle gives simultaneously the Lagrange equations of motion and the Jacobi variational equations for the system. The
A.L. Salas-Brito +8 more
core +1 more source
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Auxiliary Principle for Generalized Strongly Nonlinear Mixed Variational-Like Inequalities
We introduce and study a class of generalized strongly nonlinear mixed variational-like inequalities, which includes several classes of variational inequalities and variational-like inequalities as special cases.
Zeqing Liu +3 more
doaj +2 more sources
Some Aspects of Extended General Variational Inequalities
Noor (“Extended general variational inequalities,” 2009, “Auxiliary principle technique for extended general variational inequalities,” 2008, “Sensitivity analysis of extended general variational inequalities,” 2009, “Projection iterative methods for ...
Muhammad Aslam Noor
doaj +1 more source
Variational Integrators in Holonomic Mechanics
Variational integrators for dynamic systems with holonomic constraints are proposed based on Hamilton’s principle. The variational principle is discretized by approximating the generalized coordinates and Lagrange multipliers by Lagrange polynomials, by ...
Shumin Man, Qiang Gao, Wanxie Zhong
doaj +1 more source
Evolutionary dynamics from a variational principle
We demonstrate with a thought experiment that fitness-based population dynamical approaches to evolution are not able to make quantitative, falsifiable predictions about the long-term behavior of evolutionary systems. A key characteristic of evolutionary
Hanel, Rudolf +2 more
core +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Critical Point Theorems for Nonlinear Dynamical Systems and Their Applications
We present some new critical point theorems for nonlinear dynamical systems which are generalizations of Dancš-Hegedüs-Medvegyev's principle in uniform spaces and metric spaces by applying an abstract maximal element principle established ...
Wei-Shih Du
doaj +2 more sources

