Results 61 to 70 of about 21,521 (260)

Iterative Schemes for a Class of Mixed Trifunction Variational Inequalities

open access: yesJournal of Applied Mathematics, 2012
We use the auxiliary principle technique to suggest and analyze some iterative methods for solving a new class of variational inequalities, which is called the mixed trifunction variational inequality.
Muhammad Aslam Noor   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A parametric variational principle and residuality [PDF]

open access: yes, 2009
We prove a parametric version of a smooth convex variational principle with constraints using a Baire category approach.
Robert Deville   +3 more
core   +1 more source

Critical Point Theorems for Nonlinear Dynamical Systems and Their Applications

open access: yesFixed Point Theory and Applications, 2010
We present some new critical point theorems for nonlinear dynamical systems which are generalizations of Dancš-Hegedüs-Medvegyev's principle in uniform spaces and metric spaces by applying an abstract maximal element principle established ...
Wei-Shih Du
doaj   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Variational inclusions problems with applications to Ekeland variational principle ,fixed point and optimization problems [PDF]

open access: yes, 2011
[[abstract]]In this paper, we prove the existence theorems of two types of systems of variational inclusions problem. From these existence results, we establish Ekeland’s variational principle on topological vector space, existence theorems of common ...
L. J. Lin
core  

A parametrized variational principle of nonlinear piezoelectricity

open access: yesComputer Assisted Methods in Engineering and Science, 2023
The variational theory is the theoretical basis of the finite element method, meshfree particle methods and other modern numerical techniques. The present paper establishes a family of variational principles for nonlinear piezoelectricity.
Ji-Huan He
doaj  

Aspects of the Schwinger Variational Principle Formulation

open access: yesTrends in Computational and Applied Mathematics, 2000
The application of the Schwinger variational principle-SVP and, in particular, the second Born approximation to the evaluation of scattering amplitude and integral cross sections for eletron-atom impact is ...
J.L.S. Lino   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

A variational principle for boundary-value problems with non-linear boundary conditions

open access: yesElectronic Journal of Differential Equations, 2015
In this article, we establish a variational principle for a class of boundary-value problems with a suitable non-linear boundary conditions. As an application of the variational principle, we study the existence of classical solutions for boundary ...
Dianwu Yang
doaj  

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