Low prevalence of Borna disease virus 1 (BoDV-1) IgG antibodies in humans from areas endemic for animal Borna disease of Southern Germany. [PDF]
Borna disease virus-1 (BoDV-1) was recently discovered as cause of severe and often fatal encephalitis in humans. BoDV-1 is known to cause neurological disease in horses and sheep mainly in South and Central Germany.
Tappe D +11 more
europepmc +3 more sources
Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein. [PDF]
The phosphoprotein is an essential component of the replication complex in bornaviruses. Here, using X‐ray crystallography, the structure of the phosphoprotein from Borna disease virus 1 is presented and its flexibility in solution is characterized.Bornaviruses are RNA viruses with a mammalian, reptilian, and avian host range.
Whitehead JD, Grimes JM, Keown JR.
europepmc +2 more sources
Development of a nonhuman primate model for mammalian bornavirus infection. [PDF]
Until recently, it was assumed that members of the family Bornaviridae could not induce severe disease in humans. Today, however, Borna disease virus 1 (BoDV-1), as well as the more recently emerged variegated squirrel bornavirus 1 (VSBV-1), are known as
Schlottau K +17 more
europepmc +2 more sources
ICTV Virus Taxonomy Profile: Bornaviridae. [PDF]
Members of the family Bornaviridae produce enveloped virions containing a linear negative-sense non-segmented RNA genome of about 9 kb. Bornaviruses are found in mammals, birds, reptiles and fish.
Rubbenstroth D +10 more
europepmc +2 more sources
Avian Bornaviral Ganglioneuritis: Current Debates and Unanswered Questions. [PDF]
Avian bornaviral ganglioneuritis, often referred to as parrot wasting disease, is associated with a newly discovered avian virus from the taxonomic family Bornaviridae. Research regarding the pathogenesis and treatment for this disease is ongoing, with implications for understanding other emerging human and nonhuman diseases, as well as the health and ...
Boatright-Horowitz SL.
europepmc +2 more sources
Clinical analysis of Bornavirus Encephalitis cases demonstrates a small time window for Etiological Diagnostics and treatment attempts, a large case series from Germany 1996-2022. [PDF]
The emerging zoonotic Borna disease virus 1 (BoDV-1) and the variegated squirrel bornavirus 1 (VSBV-1) cause severe and fatal human encephalitis in Germany.
Pörtner K +5 more
europepmc +2 more sources
New World camelids are sentinels for the presence of Borna disease virus
Abstract Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV‐1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured white‐toothed shrew (Crocidura leucodon) was identified as a persistently infected species involved in virus transmission.
Alexandra J. Malbon +12 more
wiley +1 more source
Post COVID‐19: a solution scan of options for preventing future zoonotic epidemics
ABSTRACT The crisis generated by the emergence and pandemic spread of COVID‐19 has thrown into the global spotlight the dangers associated with novel diseases, as well as the key role of animals, especially wild animals, as potential sources of pathogens to humans.
Silviu O. Petrovan +24 more
wiley +1 more source
Bornaviruses in naturally infected Psittacus erithacus in Portugal: insights of molecular epidemiology and ecology. [PDF]
Background: The genus Orthobornavirus comprises non-segmented, negative-stranded RNA viruses able to infect humans, mammals, reptiles and various birds.
Pinto MC +5 more
europepmc +2 more sources
Exemplary investigations of squirrels and shrews as relevant virus reservoir hosts [PDF]
Rodents and other small mammals, such as shrews, are important reservoirs for numerous zoonotic pathogens. In addition, also various non-zoonotic agents such as polyomaviruses and herpesviruses have been described in these species. The development and
Schulze, Vanessa
core +6 more sources

