Results 41 to 50 of about 642,033 (312)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Secant varieties of adjoint varietie

Matemática Contemporânea, 1998
The adjoint varieties of this paper are certain varieties obtained from the adjoint representation of a connected simple algebraic group -- they have nothing to do with the adjoints of classical algebraic geometry. It is shown that these adjoint varieties provide examples of varieties with degenerate secant varieties. The main results of the paper are:
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FREGEAN VARIETIES

International Journal of Algebra and Computation, 2009
A class [Formula: see text] of algebras with a distinguished constant term 0 is called Fregean if congruences of algebras in [Formula: see text] are uniquely determined by their 0–cosets and ΘA (0,a) = ΘA (0,b) implies a = b for all [Formula: see text]. The structure of Fregean varieties is investigated. In particular it is shown that every congruence
Idziak, Paweł, Słomczyńska, Katarzyna, Wroński, Andrzej   +2 more
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Schubert varieties, toric varieties and ladder determinantal varieties [PDF]

Annales de l'Institut Fourier, 1997
We construct certain normal toric varieties (associated to finite distributive lattices) which are degenerations of the Grassmannians. We also determine the singular loci for certain normal toric varieties, namely the ones which are certain ladder determinantal varieties.
Gonciulea, Nicolae, Lakshmibai, Venkatramani   +1 more
openaire   +2 more sources

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Osculating Varieties of Veronese Varieties and Their Higher Secant Varieties [PDF]

Canadian Journal of Mathematics, 2007
AbstractWe consider the k-osculating varieties Ok,n.d to the (Veronese) d-uple embeddings of ℙn. We study the dimension of their higher secant varieties via inverse systems (apolarity). By associating certain 0-dimensional schemes Y ⊂ ℙn to and by studying their Hilbert functions, we are able, in several cases, to determine whether those secant ...
A. BERNARDI, CATALISANO, MARIA VIRGINIA, A. GIMIGLIANO, M. IDA'   +3 more
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Quiver Varieties, Category O for Rational Cherednik Algebras, and Hecke Algebras [PDF]

, 2008
We relate the representations of the rational Cherednik algebras associated with the complex reflection group S-n x (mu e)(n) to sheaves on Nakajima quiver varieties associated with extended Dynkin graphs via a Z-algebra construction.
Gordon, I. G.
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Representation Varieties and Character Varieties

Publications of the Research Institute for Mathematical Sciences, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source