Results 111 to 120 of about 127,752 (316)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Theorems of Birkhoff type in pseudovarieties and e-varieties of regular semi-groups
, 1998 This thesis is concerned with the problem of being able to use, or generalize, Birkhoff's fundamental theorems for classes of algebras which do not form varieties - particularly in pseudovarieties and e-varieties.
Churchill, Genevieve (15933056)
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On the Chow Groups of Supersingular Varieties
, 2002 We compute the rational Chow groups of supersingular abelian varieties and some other related varieties, such as supersingular Fermat varieties and supersingular K3 surfaces.
Najmuddin Fakhruddin
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tilting modules for reductive algebraic groups: characters and support varieties
26 pagesThese notes are our contribution to the Proceedings of the ICM 2026. We discuss some results we have obtained (in part jointly with coauthors) regarding the representation theory of reductive algebraic groups over algebraically closed fields of ...
Riche, Simon, Achar, Pramod N.
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Cytometric and genetic analysis of Slovenian local apple genotypes
BMC Plant BiologyBackground The genetic diversity and ploidy of apple varieties in Slovenia is not well known so far. In this study, a total of 233 genotypes and 8 reference varieties were analysed with a set of 15 SSR markers in order to estimate the genetic diversity ...
Kristina Gostinčar +3 more
doaj +1 more source
Geometry of Character Varieties of Surface Groups
, 2007 This article is based on a talk delivered at the RIMS--OCAMI Joint International Conference on Geometry Related to Integrable Systems in September, 2007.
Mulase, Motohico
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source