Results 61 to 70 of about 14,417 (236)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Searching for Rational Points on Varieties over Global Fields

open access: yes, 2010
The celebrated Hilbert\u27s 10th problem asks for an algorithm to decide whether a system of polynomial equations with integer coefficients has a nontrivial solution. A famous theorem of Y.
Fukshansky, Lenny
core  

The Arithmetic and Geometry of a Class of Algebraic Surfaces of General Type and Geometric Genus One [PDF]

open access: yes, 2010
We study of a class of algebraic surfaces of general type and geometric genus one, with a view toward arithmetic results. These surfaces, called CC surfaces here, have been classified over the complex numbers by Catanese and Ciliberto.
Lyons, Christopher Michael
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Isotropy of quadratic forms over function fields

open access: yes, 2019
The Hasse-Minkowski theorem says that a quadratic form over a global field admits a nontrivial zero if it admits a nontrivial zero everywhere locally.
Auel, Asher
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Corporate social responsibility (CSR) in transnational spaces: an institutionalist deconstruction of MNC's CSR practices in the Nigerian oil and gas sector [PDF]

open access: yes, 2008
Drawing from the varieties of capitalism theoretical framework, the study explores the home country influences of MNCs on their CSR practices when they operate outside their national/regional institutional contexts.
Amaeshi, Kenneth, Amao, Olufemi O.
core  

The Gross-Zagier-Zhang formula over function fields

open access: yes, 2022
We prove the Gross-Zagier-Zhang formula over global function fields of arbitrary characteristics. It is an explicit formula which relates the Neron-Tate heights of CM points on abelian varieties and central derivatives of associated quadratic base change
Qiu, Congling
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

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