Results 71 to 80 of about 14,417 (236)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

On a generalization of the support problem of Erdös and its analogues for abelian varieties and K-theory

open access: yes, 2010
In this paper we consider certain local–global principles for groups like S-units, abelian varieties over number fields and odd algebraic K-theory groups of number ...
Barańczuk, Stefan
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

The Gross-Zagier-Zhang formula over function fields

open access: yes, 2020
We prove the Gross-Zagier-Zhang formula over global function fields of arbitrary characteristics. It is an explicit formula which relates the Néron-Tate heights of CM points on abelian varieties and central derivatives of associated quadratic base change
Qiu, Congling
core  

Definable transformation to normal crossings over Henselian fields with separated analytic structure [PDF]

open access: yes, 2019
We are concerned with rigid analytic geometry in the general setting of Henselian fields K with separated analytic structure, whose theory was developed by Cluckers-Lipshitz-Robinson.
Nowak, Krzysztof, Krzysztof Jan Nowak
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

The Brauer–Manin obstruction for subvarieties of abelian varieties over function fields. ArXiv math.NT/0612263

open access: yes, 2006
. We prove that for a large class of subvarieties of abelian varieties over global function fields, the Brauer-Manin condition on adelic points cuts out exactly the rational points.
Felipe Voloch, Bjorn Poonen, José
core  

Point counting on Igusa varieties for function fields

open access: yes
Igusa varieties over the special fibre of Shimura varieties have demonstrated many applications to the Langlands program via Mantovan's formula and Shin's point counting method.
Kim, Wansu, Hamacher, Paul
core   +2 more sources

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

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