Results 11 to 20 of about 26,969 (280)

Smallpox Vaccination of Laboratory Workers at US Variola Testing Sites

open access: yesEmerging Infectious Diseases, 2015
To evaluate the need to revaccinate laboratory workers against smallpox, we assessed regular revaccination at the US Laboratory Response Network’s variola testing sites by examining barriers to revaccination and the potential for persistence of immunity.
Sharon Medcalf   +8 more
doaj   +1 more source

Struggling to a monumental triumph : Re-assessing the final stages of the smallpox eradication program in India, 1960-1980 [PDF]

open access: yes, 2007
The global smallpox program is generally presented as the brainchild of a handful of actors from the WHO headquarters in Geneva and at the agency's regional offices.
Basu, R. N   +33 more
core   +2 more sources

Serological studies on an outbreak of smallpox in the State of Bahia - Brazil in 1969

open access: yesMemorias do Instituto Oswaldo Cruz, 1972
Four weeks after Containment Vaccination undertaken against the largest outbreak of smallpox occured in Brazil in 1969, that of the municipality of Utinga, Bahia, 99 samples of serum were collected from the local population. These samples were classified
Eduardo de Azeredo Costa   +3 more
doaj   +1 more source

Development of CMX001 for the Treatment of Poxvirus Infections

open access: yesViruses, 2010
CMX001 (phosphonic acid, [[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]mono[3-(hexadecyloxy)propyl] ester) is a lipid conjugate of the acyclic nucleotide phosphonate, cidofovir (CDV).
George Painter   +10 more
doaj   +1 more source

From actually toxic to highly specific – novel drugs against poxviruses [PDF]

open access: yes, 2007
The potential use of variola virus, the causative agent of smallpox, as a bioweapon and the endemic presence of monkeypox virus in Africa demonstrate the need for better therapies for orthopoxvirus infections. Chemotherapeutic approaches to control viral
Sliva, Katja, Schnierle, Barbara
core   +2 more sources

Poxvirus Viability and Signatures in Historical Relics

open access: yesEmerging Infectious Diseases, 2014
Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence ...
Andrea M. McCollum   +7 more
doaj   +1 more source

Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?

open access: yesEmerging Infectious Diseases, 2011
In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
doaj   +1 more source

Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]

open access: yesPLoS ONE, 2015
Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates   +5 more
doaj   +1 more source

Characterization of Two Historic Smallpox Specimens from a Czech Museum

open access: yesViruses, 2017
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer   +22 more
doaj   +1 more source

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