Results 101 to 110 of about 10,893 (204)
Ankyrin-like proteins of variola and vaccinia viruses
Computer analysis of full coding sequences of variola major virus strain India-1967 genome and vaccinia virus strain Copenhagen genome have been carried out.
Lev S. Sandakhchiev +5 more
core +1 more source
This article evaluates the scientific and commercial rationales for the synthesis of horsepox virus. I find that the claimed benefits of using horsepox virus as a smallpox vaccine rest on a weak scientific foundation and an even weaker business case that
Gregory D. Koblentz
doaj +1 more source
The Variola Virus: The Threat of Reintroduction and Our Capacity to Respond
Though eradicated in 1980, smallpox remains a top priority pathogen due to the threat of a deliberate or accidental reintroduction of the Variola major virus. This thesis represents a thorough assessment of this threat, grounded in the molecular virology
Forsgren, Seth
core
Variola virus topoisomerase: DNA cleavage specificity and distribution of sites in Poxvirus genomes
Topoisomerase enzymes regulate superhelical tension in DNA resulting from transcription, replication, repair, and other molecular transactions. Poxviruses encode an unusual type IB topoisomerase that acts only at conserved DNA sequences containing the ...
Lefkowitz, Elliot J. +7 more
core +1 more source
The specificity of variola virus-specific RNA in situ hybridization (ISH).
A) variola virus (VARV) RNA was detected in the tongue tissue of a cynomolgus macaque, (placebo-treated #9) that succumbed to intravenous exposure of VARV using RNA ISH.
Dennis E. Hruby (17691646) +12 more
core +1 more source
Genome Sequence Diversity and Clues to the Evolution of Variola (Smallpox) Virus
Comparative genomics of 45 epidemiologically varied variola virus isolates from the past 30 years of the smallpox era indicate low sequence diversity, suggesting that there is probably little difference in the isolates' functional gene content ...
Esposito, J. J.
core +1 more source
Biological threat agents such as Bacillus anthracis, Variola virus, and botulinum toxin pose serious risk to national security and public health due to their high transmissibility, lethality, and potential for weaponization.
Jungeun Lee
doaj +1 more source
Perioral Molluscum Contagiosum- Report of 2 Cases in HIV Seropositive Patients
Molluscum contagiosum (MC) is a mucocutaneous disorder caused by DNA virus of the Pox family affecting both the children and adults. MCV remains by far the most common pox viral pathogen for humans after the eradication of Small pox variola virus (1 ...
K T Magesh, N Malathi, S Anandan
doaj
Enfrentando el bioterrorismo: aspectos epidemiológicos, clínicos y preventivos de la viruela
Uno de los grandes logros de la salud pública mundial, la erradicación de la viruela, puede verse mermado por el posible riesgo de bioterrorismo. El debate acerca de la destrucción de los restos del virus en los dos laboratorios de referencia de la ...
Franco-Paredes Carlos +5 more
doaj
Characteristics of cowpox virus isolates and orthopoxvirus reference strains.
CPXV: cowpox virus, VACV: vaccinia virus, CMLV: camelpox virus, MPXV: monkeypox virus, ECTV: ectromelia virus, VARV: variola virus.nk: not known.
Martin Straube (370779) +5 more
core +1 more source

