Results 101 to 110 of about 15,071 (221)
Terminal Region Sequence Variations in Variola Virus DNA
Genome DNA terminal region sequences were determined for a Brazilian alastrim variola minor virus strain Garcia-1966 that was associated with an 0.8% case-fatality rate and African smallpox strains Congo-1970 and Somalia-1977 associated with variola major (9.6%) and minor (0.4%) mortality rates, respectively.
MASSUNG, ROBERT F. +9 more
openaire +2 more sources
Viral detection by electron microscopy: past, present and future. [PDF]
International audienceViruses are very small and most of them can be seen only by TEM (transmission electron microscopy). TEM has therefore made a major contribution to virology, including the discovery of many viruses, the diagnosis of various viral ...
Ait-Goughoulte +92 more
core +3 more sources
Alastrim Smallpox Variola Minor Virus Genome DNA Sequences
Alastrim variola minor virus, which causes mild smallpox, was first recognized in Florida and South America in the late 19th century. Genome linear double-stranded DNA sequences (186,986 bp) of the alastrim virus Garcia-1966, a laboratory reference strain from an outbreak associated with 0.8% case fatalities in Brazil in 1966, were determined except ...
Shchelkunov, Sergei N. +9 more
openaire +2 more sources
False positives complicate ancient pathogen identifications using high-throughput shotgun sequencing [PDF]
Background: Identification of historic pathogens is challenging since false positives and negatives are a serious risk. Environmental non-pathogenic contaminants are ubiquitous.
Campana, Michael G +3 more
core +3 more sources
Analysis of variola virus molecular evolution suggests an old origin of the virus consistent with historical records. [PDF]
Forni D +4 more
europepmc +1 more source
Analysing Leadership in Global Health Governance [PDF]
Rhetoric around the need for more and better leadership is everywhere in contemporary global health governance, yet there has been little articulation of what type of leadership is required, who might play leadership roles, and in what fora leadership ...
HARMAN, S, RUSHTON, S
core
Progrès scientifiques et nouvelles armes biologiques [PDF]
Les armes biologiques sont différentes des armes conventionnelles, car les germes vivants détiennent un extraordinaire et imprévisible potentiel de multiplication, de propagation et de variation génétique au cours de leur diffusion dans une population ...
Berche, Patrick
core +1 more source
In 2007, the United States– Food and Drug Administration (FDA) issued guidance concerning animal models for testing the efficacy of medical countermeasures against variola virus (VARV), the etiologic agent for smallpox.
Jennifer Garver +7 more
doaj +1 more source
Topography of Variola Smallpox Virus Inverted Terminal Repeats
We examined the nucleotide sequences of the inverted terminal repeat (ITR) regions adjacent to the covalently closed hairpin end sequences of three variola major and four minor strains from smallpox outbreaks in Europe, Asia, Africa, and South America.
Massung, Robert F. +2 more
openaire +2 more sources
Poxvirus-encoded TNF decoy receptors inhibit the biological activity of transmembrane TNF [PDF]
© 2015 The Authors. Poxviruses encode up to four different soluble TNF receptors, named cytokine response modifier B (CrmB), CrmC, CrmD and CrmE. These proteins mimic the extracellular domain of the cellular TNF receptors to bind and inhibit the activity
Alcamí, Antonio +2 more
core +1 more source

