Results 101 to 110 of about 10,893 (204)

Ankyrin-like proteins of variola and vaccinia viruses

open access: yes, 1993
Computer analysis of full coding sequences of variola major virus strain India-1967 genome and vaccinia virus strain Copenhagen genome have been carried out.
Lev S. Sandakhchiev   +5 more
core   +1 more source

A Critical Analysis of the Scientific and Commercial Rationales for the De Novo Synthesis of Horsepox Virus

open access: yesmSphere, 2018
This article evaluates the scientific and commercial rationales for the synthesis of horsepox virus. I find that the claimed benefits of using horsepox virus as a smallpox vaccine rest on a weak scientific foundation and an even weaker business case that
Gregory D. Koblentz
doaj   +1 more source

The Variola Virus: The Threat of Reintroduction and Our Capacity to Respond

open access: yes, 2014
Though eradicated in 1980, smallpox remains a top priority pathogen due to the threat of a deliberate or accidental reintroduction of the Variola major virus. This thesis represents a thorough assessment of this threat, grounded in the molecular virology
Forsgren, Seth
core  

Variola virus topoisomerase: DNA cleavage specificity and distribution of sites in Poxvirus genomes

open access: yes, 2007
Topoisomerase enzymes regulate superhelical tension in DNA resulting from transcription, replication, repair, and other molecular transactions. Poxviruses encode an unusual type IB topoisomerase that acts only at conserved DNA sequences containing the ...
Lefkowitz, Elliot J.   +7 more
core   +1 more source

The specificity of variola virus-specific RNA in situ hybridization (ISH).

open access: yes
A) variola virus (VARV) RNA was detected in the tongue tissue of a cynomolgus macaque, (placebo-treated #9) that succumbed to intravenous exposure of VARV using RNA ISH.
Dennis E. Hruby (17691646)   +12 more
core   +1 more source

Genome Sequence Diversity and Clues to the Evolution of Variola (Smallpox) Virus

open access: yes, 2006
Comparative genomics of 45 epidemiologically varied variola virus isolates from the past 30 years of the smallpox era indicate low sequence diversity, suggesting that there is probably little difference in the isolates' functional gene content ...
Esposito, J. J.
core   +1 more source

Biological threat preparedness through vaccine development and stockpiling: challenges and strategic implications

open access: yesFrontiers in Public Health
Biological threat agents such as Bacillus anthracis, Variola virus, and botulinum toxin pose serious risk to national security and public health due to their high transmissibility, lethality, and potential for weaponization.
Jungeun Lee
doaj   +1 more source

Perioral Molluscum Contagiosum- Report of 2 Cases in HIV Seropositive Patients

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2007
Molluscum contagiosum (MC) is a mucocutaneous disorder caused by DNA virus of the Pox family affecting both the children and adults. MCV remains by far the most common pox viral pathogen for humans after the eradication of Small pox variola virus (1 ...
K T Magesh, N Malathi, S Anandan
doaj  

Enfrentando el bioterrorismo: aspectos epidemiológicos, clínicos y preventivos de la viruela

open access: yesSalud Pública de México, 2003
Uno de los grandes logros de la salud pública mundial, la erradicación de la viruela, puede verse mermado por el posible riesgo de bioterrorismo. El debate acerca de la destrucción de los restos del virus en los dos laboratorios de referencia de la ...
Franco-Paredes Carlos   +5 more
doaj  

Characteristics of cowpox virus isolates and orthopoxvirus reference strains.

open access: yes, 2013
CPXV: cowpox virus, VACV: vaccinia virus, CMLV: camelpox virus, MPXV: monkeypox virus, ECTV: ectromelia virus, VARV: variola virus.nk: not known.
Martin Straube (370779)   +5 more
core   +1 more source

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