Results 91 to 100 of about 1,368,656 (159)
The Variola Virus: The Threat of Reintroduction and Our Capacity to Respond
, 2014 Though eradicated in 1980, smallpox remains a top priority pathogen due to the threat of a deliberate or accidental reintroduction of the Variola major virus. This thesis represents a thorough assessment of this threat, grounded in the molecular virology
Forsgren, Seth
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Conserved Surface-Exposed K/R-X-K/R Motifs and Net Positive Charge on Poxvirus Complement Control Proteins Serve as Putative Heparin Binding Sites and Contribute to Inhibition of Molecular Interactions with Human Endothelial Cells: a Novel Mechanism for Evasion of Host Defense [PDF]
, 2000 Vaccinia virus complement control protein (VCP) has been shown to possess the ability to inhibit both classical and alternative complement pathway activation.
Shchelkunov, SN +11 more
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Genome Sequence Diversity and Clues to the Evolution of Variola (Smallpox) Virus
, 2006 Comparative genomics of 45 epidemiologically varied variola virus isolates from the past 30 years of the smallpox era indicate low sequence diversity, suggesting that there is probably little difference in the isolates' functional gene content ...
Esposito, J. J. +15 more
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, 2015 Recently we constructed a homology model of the enzyme thymidylate kinase from Variola virus (VarTMPK) and proposed it as a new target to the drug design against smallpox.
Gonçalves, Arlan S. +6 more
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Gross differences in ORF size (nt) and complement.
, 2013 Gross differences in ORF size (nt) and complement among TT clones and four VACVs (Cop, ListerV107, Acam 2000, and WR). a: ITR, inverted terminal repeat; b: genes with unknown functions; c: CPXVBR, Cowpox virus Brighton Red; d: VARBSH, Variola major virus
Qicheng Zhang (402220) +6 more
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vi, 56 p.The WHO Advisory Committee on Variola Virus Research (ACVVR) held its twenty-fifth meeting in October 2023 to review progress in WHO-approved research involving live variola virus, assess proposals for future work, and provide recommendations ...
World Health Organization
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Variola virus genome sequenced from an eighteenth-century museum specimen supports the recent origin of smallpox. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2020 Ferrari G +8 more
europepmc +1 more source
Isolation of smallpox virus from the nasopharynx of patients with variola sine eruptione
, 1952 In 2 out of 13 contacts of smallpox patients, variola virus was recovered from nasopharyngeal secretions on the 14th and the 18th day after the last contact.
Verlinde, J.D., Tongeren, H.A.E. van
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Neutralization of viral infection with VIG.
, 2015 Vaccinia Immune Globulin was titrated in 3-fold serial dilutions starting from 1:50 dilution (66.67 IU/mL) and was pre-incubated for 30 minutes at 37°C with test virus (cowpox, vaccinia or monkeypox viruses), or at 35.5°C for variola virus. Pre-incubated
Victoria Olson (210647) +5 more
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7 pThe article summarizes the proceedings and outcomes of the 26th meeting of the WHO Advisory Committee on Variola Virus Research, held in November 2024 to review progress in research supporting global preparedness for the potential re-emergence of ...
World Health Organization = Organisation mondiale de la Santé
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