Results 91 to 100 of about 10,893 (204)
Virus biosafety and biodefense category list comparison.
, 2014 aSmallpox is caused by Variola viruses. Variola viruses including Variola major which causes disease with serious clinical symptoms and Variola minor (alastrim) which causes disease with less severe clinical symptoms.
Deqiao Tian (590816), Tao Zheng (146941)
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In vitro characterization of a nineteenth-century therapy for smallpox.
PLoS ONE, 2012 In the nineteenth century, smallpox ravaged through the United States and Canada. At this time, a botanical preparation, derived from the carnivorous plant Sarracenia purpurea, was proclaimed as being a successful therapy for smallpox infections.
William Arndt +9 more
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Viruses, 2016 In 2007, the United States– Food and Drug Administration (FDA) issued guidance concerning animal models for testing the efficacy of medical countermeasures against variola virus (VARV), the etiologic agent for smallpox.
Jennifer Garver +7 more
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, 2007 Includes bibliographical references (leaves 96-114).Cowpox virus has been found to encode the inflammation modulatory protein (IMP) (Miller, C.G., 1997), a homologue vaccinia virus complement control protein (VCP). VCP belongs to regulation of complement
Paulsen, Janis
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Analysis of variola virus molecular evolution suggests an old origin of the virus consistent with historical records. [PDF]
Microb Genom, 2023 Forni D +4 more
europepmc +1 more source
[The variola virus as a biological weapon].
Lijecnicki vjesnik, 2003 In view of the threat of use of the variola virus as a biological weapon, the interest of medical and other public in this causative agent that was eradicated in the wild at the end of the 1970s has increased. The paper gives an outline of the current knowledge on biological properties of the variola virus, and on the epidemiology, pathogenesis ...
Gordana, Mlinarić-Galinović +3 more
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Genes of variola and vaccinia viruses necessary to overcome the host protective mechanisms
, 1993 Analysis of variola virus nucleotide sequence revealed proteins belonging to several families which provide the virus with the possibility of overcoming the barriers of specific and non-specific host defence against viral infection.
Lev S. Sandakhchiev +5 more
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Poxvirus Viability and Signatures in Historical Relics
Emerging Infectious Diseases, 2014 Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence ...
Andrea M. McCollum +7 more
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Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus. [PDF]
PLoS Pathog, 2021 Hutson CL +13 more
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Detection of variola virus infection using molecular techniques.
A-B) Variola virus (VARV) antigen (brown in A) and RNA (red in B) were detected in the haired skin of NHP #13, a placebo-treated cynomolgus macaque that succumbed to VARV exposure; immunohistochemistry (IHC) and RNA in situ hybridization (ISH ...
Dennis E. Hruby (17691646) +12 more
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