Results 71 to 80 of about 10,185 (170)

Thermo-Efficient Strains of Variola Major Virus

Journal of General Virology, 1967
Thermo-efficient and thermo-sensitive mutants of pox viruses are obtained, without the aid of mutagens, only with difficulty. Kirn and his colleagues (1, 2) have described both a thermo-sensitive and a thermo-efficient mutant of vaccinia virus. This note reports the derivation and properties of two thermo-efficient strains of variola major virus.
K R, Dumbell, H S, Bedson, M, Nizamuddin
openaire   +2 more sources

In vitro characterization of a nineteenth-century therapy for smallpox.

PLoS ONE, 2012
In the nineteenth century, smallpox ravaged through the United States and Canada. At this time, a botanical preparation, derived from the carnivorous plant Sarracenia purpurea, was proclaimed as being a successful therapy for smallpox infections.
William Arndt, Chandra Mitnik, Karen L Denzler, Stacy White, Robert Waters, Bertram L Jacobs, Yvan Rochon, Victoria A Olson, Inger K Damon, Jeffrey O Langland   +9 more
doaj   +1 more source

Ectromelia Virus Disease Characterization in the BALB/c Mouse: A Surrogate Model for Assessment of Smallpox Medical Countermeasures

Viruses, 2016
In 2007, the United States– Food and Drug Administration (FDA) issued guidance concerning animal models for testing the efficacy of medical countermeasures against variola virus (VARV), the etiologic agent for smallpox.
Jennifer Garver, Lauren Weber, Eric M. Vela, Mike Anderson, Richard Warren, Michael Merchlinsky, Christopher Houchens, James V. Rogers   +7 more
doaj   +1 more source

Analysis of variola virus molecular evolution suggests an old origin of the virus consistent with historical records. [PDF]

Microb Genom, 2023
Forni D, Molteni C, Cagliani R, Clerici M, Sironi M.   +4 more
europepmc   +1 more source

Misinformation and women's health: Rebuilding trust in evidence‐based care

International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1632-1633, June 2026.
Zainab Al‐Jawahiri
wiley   +1 more source

In Silico Studies of Potential Selective Inhibitors of Thymidylate Kinase from Variola virus. [PDF]

Pharmaceuticals (Basel), 2021
Garcia DR, Souza FR, Guimarães AP, Valis M, Pavelek Z, Kuca K, Ramalho TC, França TCC.   +7 more
europepmc   +1 more source

Poxvirus Viability and Signatures in Historical Relics

Emerging Infectious Diseases, 2014
Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence ...
Andrea M. McCollum, Yu Li, Kimberly Wilkins, Kevin L. Karem, Whitni B. Davidson, Christopher D. Paddock, Mary G. Reynolds, Inger K. Damon   +7 more
doaj   +1 more source

Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus. [PDF]

PLoS Pathog, 2021
Hutson CL, Kondas AV, Ritter JM, Reed Z, Ostergaard SD, Morgan CN, Gallardo-Romero N, Tansey C, Mauldin MR, Salzer JS, Hughes CM, Goldsmith CS, Carroll D, Olson VA.   +13 more
europepmc   +1 more source

An Early Record of Photochemotherapy for Vitiligo by Rhazes (865–925 ce) in Liber Continens

JEADV Clinical Practice, Volume 5, Issue 2, Page 684-685, June 2026.
Alireza Tavakkoli
wiley   +1 more source

A Critical Analysis of the Scientific and Commercial Rationales for the De Novo Synthesis of Horsepox Virus

mSphere, 2018
This article evaluates the scientific and commercial rationales for the synthesis of horsepox virus. I find that the claimed benefits of using horsepox virus as a smallpox vaccine rest on a weak scientific foundation and an even weaker business case that
Gregory D. Koblentz
doaj   +1 more source