Results 51 to 60 of about 10,185 (170)

Acute Late-Stage Myocarditis in the Crab-Eating Macaque Model of Hemorrhagic Smallpox

Viruses, 2021
Hemorrhagic smallpox, caused by variola virus (VARV), was a rare but nearly 100% lethal human disease manifestation. Hemorrhagic smallpox is frequently characterized by secondary bacterial infection, coagulopathy, and myocardial and subendocardial ...
Reed F. Johnson, Lauren A. Keith, Timothy K. Cooper, Srikanth Yellayi, Nicole M. Josleyn, Krisztina B. Janosko, James D. Pettitt, David Thomasson, Katie R. Hagen, Robin Gross, John G. Bernbaum, Debbie Douglas, Jeffrey Solomon, Mark Martinez, Kurt Cooper, Marisa St. Claire, Danny R. Ragland, Peter B. Jahrling, Jens H. Kuhn, Andrew E. Arai   +19 more
doaj   +1 more source

Knowledge and Attitudes of Healthcare Workers Toward the Re‐Emergence of Human Monkeypox Virus Infection in Public Health Facilities in the Central Ethiopia Region: An Online Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Human monkeypox (mpox) is a re‐emerging zoonotic viral disease in Africa. Despite recent reports in Ethiopia, no studies have assessed healthcare workers' (HCWs) knowledge and attitudes in the Central Ethiopia Region. This study aimed to determine HCWs knowledge and attitudes toward the re‐emergence of mpox in public health
Yilma Markos Larebo, Zerfework Debebe Argago, Markos Selamu Jifar, Abebe Alemu Anshebo, Sujit Kumar Behera, Natarajan Gopalan   +5 more
wiley   +1 more source

The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and resilient supply chains. Management focuses on supportive care, infection prevention, and accurate diagnosis, with pharmacists ensuring the availability and rational use of vaccines, disinfectants ...
Ayalew Sirbemo Degebo, Fisseha Assegidew Gebretsadik, Abyou Seyfu Ambaye, Bedilu Linger Endalifer, Teshome Fentik Belachew   +4 more
wiley   +1 more source

Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino, Marco Giuseppe Del Buono, Michele Marchetta, Nicola Potere, Aldo Bonaventura, Alessandra Vecchiè, Danilo Malandrino, Giacomo Emmi, Jordana Kron, Antonio Abbate   +9 more
wiley   +1 more source

Smallpox in the Post-Eradication Era

Viruses, 2020
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Hermann Meyer, Rosina Ehmann, Geoffrey L. Smith   +2 more
doaj   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, Volume 9, Issue 7, Page 1310-1324, July 2026.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics

Viruses, 2010
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller, Jill Schriewer, George Painter, Akbar M. Siddiqui, Scott Parker   +4 more
doaj   +1 more source

Severe Scrotal Cellulitis in a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Vera Al Baaklini, Dima Jeha, Alfred Ammoury   +3 more
wiley   +1 more source

Durability of the Humoral Response to MPXV Infection

Journal of the International AIDS Society, Volume 29, Issue S2, July 2026.
ABSTRACT Introduction Mpox virus (MPXV) re‐emerged in endemic countries in recent decades, resulting in large outbreaks in central and western Africa and a worldwide epidemic of clade IIb MPXV starting in 2022. Mpox cases in vaccinated persons, and a few documented reinfections, have raised questions about the durability of MPXV humoral immunity ...
Tara N. Palmore
wiley   +1 more source

Discovery and Structural Characterization of a Highly Protective Neutralizing Antibody Targeting the Mpox Virus A35R Protein

MedComm, Volume 7, Issue 7, July 2026.
High‐affinity monoclonal antibodies (mAbs) targeting the MPXV EEV protein A35R were rapidly isolated using mRNA‐LNP vaccination and the Beacon single‐cell sorting Optofluidic platform, followed by functional profiling. One mAb, 17H1, potently neutralized authentic MPXV and conferred complete protection in vivo.
Shimeng Bai, Shuo Song, Xin Wang, Yuxin Xiao, Yun Long, Fenfang Wu, Fuxiang Wang, Zhongyi Fan, Jianqing Xu, Maozhou He, Hongzhou Lu   +10 more
wiley   +1 more source