Acute Late-Stage Myocarditis in the Crab-Eating Macaque Model of Hemorrhagic Smallpox
Hemorrhagic smallpox, caused by variola virus (VARV), was a rare but nearly 100% lethal human disease manifestation. Hemorrhagic smallpox is frequently characterized by secondary bacterial infection, coagulopathy, and myocardial and subendocardial ...
Reed F. Johnson +19 more
doaj +1 more source
Abordamos el presente trabajo con el objetivo de realizar una revisión bibliográfica que nos permita elaborar un análisis del empleo de armas biológicas tanto en el pasado, es decir, una documentación de la utilización de éstas a lo largo de la historia,
Bruhn Cuevas, Rosa María
core +1 more source
Are We Prepared in Case of a Possible Smallpox-Like Disease Emergence?
Smallpox was the first human disease to be eradicated, through a concerted vaccination campaign led by the World Health Organization. Since its eradication, routine vaccination against smallpox has ceased, leaving the world population susceptible to ...
Victoria A. Olson, Sergei N. Shchelkunov
doaj +1 more source
An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses
The ongoing worldwide monkeypox outbreak is caused by viral lineages (globally referred to as hMPXV1) that are related to but distinct from clade IIb MPXV viruses transmitted within Nigeria.
Diego Forni +3 more
doaj +1 more source
Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner +2 more
wiley +1 more source
Biological warfare: The many possibilities
Biological warfare has been a threat to society for many decades. This article summarises some of the most likely organisms suitable for a bio-terrorist attack, including Bacillus anthracis, Francisella tularensis, Yersinia pestis, the agents of viral ...
E. Wasserman
doaj +1 more source
Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk +4 more
wiley +1 more source
Immunological Memory after Exposure to Variola Virus, Monkeypox Virus, and Vaccinia Virus [PDF]
We compared cellular and humoral immunity to vaccinia virus (VV) in individuals exposed to 3 different orthopoxviruses: 154 individuals previously vaccinated with VV, 7 individuals with a history of monkeypox virus infection, and 8 individuals with a history of variola virus infection.
Sivapalasingam, Sumathi +8 more
openaire +3 more sources
Expression and functional characterisation of Variola and Monkeypox virus tumour necrosis factor receptor (TNFR) proteins [PDF]
University of Technology, Sydney. Faculty of Science.Tumour necrosis factor-a (TNFα) is a pleiotropic cytokine that plays a critical role in cellular response to virus infection. Virtually all poxviruses encode genes that are homologous to human tumour
Sherwood, S
core
A complete ancient RNA genome : identification, reconstruction and evolutionary history of archaeological Barley Stripe Mosaic Virus [PDF]
The origins of many plant diseases appear to be recent and associated with the rise of domestication, the spread of agriculture or recent global movements of crops.
Allaby, Robin G. +5 more
core +1 more source

