Results 61 to 70 of about 1,046,980 (206)

An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses

mSphere, 2023
The ongoing worldwide monkeypox outbreak is caused by viral lineages (globally referred to as hMPXV1) that are related to but distinct from clade IIb MPXV viruses transmitted within Nigeria.
Diego Forni, Rachele Cagliani, Uberto Pozzoli, Manuela Sironi   +3 more
doaj   +1 more source

Real-Time PCR to Identify Variola Virus or Other Human Pathogenic Orthopox Viruses

, 2007
International audienceAbstract Background: Variola virus (family Poxviridae, genus Orthopoxvirus) and the closely related cowpox, vaccinia, and monkeypox viruses can infect humans.
Scaramozzino, Natale, Garin, Daniel, Ferrier-Rembert, Audrey, Favier, Anne-Laure, Rothlisberger, Corinne, Richard, Stéphane, Meyer, Hermann, Crance, Jean-Marc   +7 more
core   +1 more source

Characterisation of Typical Enteropathogenic Escherichia coli (tEPEC) and bfpA Genes From Five Bat Species Reveals Australian Pteropus Spp. Are Natural tEPEC Hosts

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This study revealed that Australia's five Pteropus bat species are all natural hosts of typical Enteropathogenic Escherichia coli (tEPEC)—historically considered a human‐specific pathogen. Across the five Pteropus spp., tEPEC prevalence ranged between 14.2% and 37.0%, with 18 bat‐specific tEPEC strain types and 24 bat‐specific bfpA allele types ...
Fiona K. McDougall, Laura A. Pulscher, Wayne S. J. Boardman, Karrie Rose, Mariel Fulham, Michelle L. Power   +5 more
wiley   +1 more source

Mpox Airborne Transmission: A Systematic Review

Reviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Since May 2022, mpox has been reported across multiple nonendemic regions, with concurrent outbreaks in diverse geographic settings, raising concerns about broader international spread. However, evidence regarding the risk of airborne transmission remains limited.
Lucas Ferreira Theotonio dos Santos, Leonardo Javier Arcuri, Viviane Aparecida R. Sant’Anna, Patrícia Campos Couto, Guilherme de Paula P. Schettino, Luiz Vicente Rizzo, Henrique Andrade R. Fonseca   +6 more
wiley   +1 more source

Effect of disinfectants on variola virus in cell culture [PDF]

Applied and Environmental Microbiology, 1976
Twenty kinds of disinfectants were examined for ability to inactivate variola virus. Cytopathic effect and plaque formation on monolayer cultures of an established monkey kidney cell line were used as indicators of virus inactivation. A micromethod using microplate cultures, and not requiring a CO2 incubator, was adopted.
I, Tanabe, S, Hotta
openaire   +2 more sources

Identification of Repurposed Drugs Against Monkeypox Virus Through Comprehensive Virtual Screening

Biotechnology Journal, Volume 21, Issue 8, August 2026.
Graphical Abstract and Lay Summary By combining interspecies protein analysis with advanced virtual screening, this study identifies potent repurposed drug candidates—including vindesine and LY2090314—targeting mpox DNA topoisomerase and polymerase. This workflow provides a rapid, practical framework for antiviral discovery against emerging infectious ...
Taeho Yu, Woo Dae Jang, Sang Yup Lee
wiley   +1 more source

Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics

Viruses, 2010
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller, Jill Schriewer, George Painter, Akbar M. Siddiqui, Scott Parker   +4 more
doaj   +1 more source

Smallpox in the Post-Eradication Era

Viruses, 2020
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Hermann Meyer, Rosina Ehmann, Geoffrey L. Smith   +2 more
doaj   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman, Karan Goel, Fernando Berton Zanchi, Aykut Ozdarendeli, Somdutt Mujwar, Ahmet E. Yetiman, Ozkan Fidan   +6 more
wiley   +1 more source

Knowledge and Attitudes of Healthcare Workers Toward the Re‐Emergence of Human Monkeypox Virus Infection in Public Health Facilities in the Central Ethiopia Region: An Online Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Human monkeypox (mpox) is a re‐emerging zoonotic viral disease in Africa. Despite recent reports in Ethiopia, no studies have assessed healthcare workers' (HCWs) knowledge and attitudes in the Central Ethiopia Region. This study aimed to determine HCWs knowledge and attitudes toward the re‐emergence of mpox in public health
Yilma Markos Larebo, Zerfework Debebe Argago, Markos Selamu Jifar, Abebe Alemu Anshebo, Sujit Kumar Behera, Natarajan Gopalan   +5 more
wiley   +1 more source