Results 81 to 90 of about 10,893 (204)

Conserved Surface-Exposed K/R-X-K/R Motifs and Net Positive Charge on Poxvirus Complement Control Proteins Serve as Putative Heparin Binding Sites and Contribute to Inhibition of Molecular Interactions with Human Endothelial Cells: a Novel Mechanism for Evasion of Host Defense

, 2000
Vaccinia virus complement control protein (VCP) has been shown to possess the ability to inhibit both classical and alternative complement pathway activation.
Shchelkunov, SN, Reynolds, DN, Kotwal, GJ, Justus, DE, Srisatjaluk, R, Loparev, VN, Totmenin, AV, Keeling, KL, Smith, SA, Parkinson, J, Barlow, PN, Mullin, NP   +11 more
core  

Readiness Level of Spanish Labs to Detect Mpox Clade Ib: A Nationwide EQA

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT To assess the preparedness and diagnostic capacity of Spanish clinical microbiology laboratories to detect the emerging monkeypox virus (MPXV) Clade Ib through a nationwide external quality assessment. A blinded 16‐sample panel (serum and DNA eluates) containing MPXV Clade Ib, Clade II, vaccinia, and negatives was distributed.
Adolfo De Salazar, Anabel Negredo, Juan Carlos Galán, Teresa Del Peso, Marta Illescas, Laura Martínez‐García, Concepción Gimeno, Federico García, María Paz Sánchez‐Seco, the QC Mpox Spain Collaborators, Sonia Algarate, Andrés Antón, Ana Milagro, Fernando Buñuel, Laura Calatayud, Pilar Catalán, Gregorio Marañón, Marta Domínguez‐Gil González, Manel Flores, Pablo Fraile, Ana Fuentes López, María del Carmen Garma, Mª Dolores Gómez‐Ruíz, Mónica Gozalo, Manuel Grau, Almudena Gutiérrez‐Arroyo, Silvia Hernáez, Águeda Hernández‐Rodríguez, Noelia Hernando, Flor Isabel Hidalgo, José Luis Juan, Eduardo Lagarejos, Miguel Julián Martínez‐Yoldi, Santiago Melón, Pablo Mendoza, Laura Merino, Milagrosa Montes, Jordi Niubó, María Dolores Ocete, Alejandra Pérez‐García, Jorge Alfredo Pérez‐García, Mercedes Pérez‐Ruiz, Sonia Pérez‐Castro, Jordi Reina, Romina Soledad Romero, Genoveva Santillana, Encarna Simarro, Mikel Urruticoechea, Laura Herrero, Francisca Molero   +49 more
wiley   +1 more source

THE STABILITY OF VARIOLA VIRUS PROPAGATED IN EMBRYONATED EGGS [PDF]

Journal of Experimental Medicine, 1943
After 24 transfers in embryonated eggs a strain of variola virus (Chinese) was established in the testis of the rabbit and maintained for 11 passages at intervals of 7 days. Residence in the rabbit testis was not accompanied by any significant alteration in the species identity of the virus.
openaire   +2 more sources

An Early Record of Photochemotherapy for Vitiligo by Rhazes (865–925 ce) in Liber Continens

JEADV Clinical Practice, Volume 5, Issue 2, Page 684-685, June 2026.
Alireza Tavakkoli
wiley   +1 more source

Expression and functional characterisation of Variola and Monkeypox virus tumour necrosis factor receptor (TNFR) proteins [PDF]

, 2012
University of Technology, Sydney. Faculty of Science.Tumour necrosis factor-a (TNFα) is a pleiotropic cytokine that plays a critical role in cellular response to virus infection. Virtually all poxviruses encode genes that are homologous to human tumour
Sherwood, S
core  

Thermo-Efficient Strains of Variola Major Virus

Journal of General Virology, 1967
Thermo-efficient and thermo-sensitive mutants of pox viruses are obtained, without the aid of mutagens, only with difficulty. Kirn and his colleagues (1, 2) have described both a thermo-sensitive and a thermo-efficient mutant of vaccinia virus. This note reports the derivation and properties of two thermo-efficient strains of variola major virus.
K R, Dumbell, H S, Bedson, M, Nizamuddin
openaire   +2 more sources

Enfrentando el bioterrorismo: aspectos epidemiológicos, clínicos y preventivos de la viruela Confronting bioterrorism: epidemiologic, clinical, and preventive aspects of smallpox

Salud Pública de México, 2003
Uno de los grandes logros de la salud pública mundial, la erradicación de la viruela, puede verse mermado por el posible riesgo de bioterrorismo. El debate acerca de la destrucción de los restos del virus en los dos laboratorios de referencia de la ...
Carlos Franco-Paredes, Carlos del Río, Margarita Nava-Frías, Sigfrido Rangel-Frausto, Ildefonso Téllez, José Ignacio Santos-Preciado   +5 more
doaj  

Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice.

PLoS Pathogens, 2015
Orthopoxviruses (OPV), including variola, vaccinia, monkeypox, cowpox and ectromelia viruses cause acute infections in their hosts. With the exception of variola virus (VARV), the etiological agent of smallpox, other OPV have been reported to persist in ...
Isaac G Sakala, Geeta Chaudhri, Anthony A Scalzo, Preethi Eldi, Timothy P Newsome, Robert M Buller, Gunasegaran Karupiah   +6 more
doaj   +1 more source

Orthopoxvirus Genome Evolution: The Role of Gene Loss

Viruses, 2010
Poxviruses are highly successful pathogens, known to infect a variety of hosts. The family Poxviridae includes Variola virus, the causative agent of smallpox, which has been eradicated as a public health threat but could potentially reemerge as a ...
Eneida L. Hatcher, Elliot J. Lefkowitz, Robert Curtis Hendrickson, Chunlin Wang   +3 more
doaj   +1 more source

Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism

Advances in Virology, 2012
In the course of evolution, viruses have developed various molecular mechanisms to evade the defense reactions of the host organism. When understanding the mechanisms used by viruses to overcome manifold defense systems of the animal organism ...
Sergei N. Shchelkunov
doaj   +1 more source