Results 41 to 50 of about 10,893 (204)

Effect of disinfectants on variola virus in cell culture [PDF]

Applied and Environmental Microbiology, 1976
Twenty kinds of disinfectants were examined for ability to inactivate variola virus. Cytopathic effect and plaque formation on monolayer cultures of an established monkey kidney cell line were used as indicators of virus inactivation. A micromethod using microplate cultures, and not requiring a CO2 incubator, was adopted.
I, Tanabe, S, Hotta
openaire   +2 more sources

Variola virus, 49 strains, 2926 SNPs (increased).

, 2013
Variola virus, 49 strains, 2926 SNPs (increased).
Wei-Bung Wang (467576), Tao Jiang (28401), Shea Gardner (87450)   +2 more
core   +1 more source

Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim [PDF]

, 2015
Subversion of host cell apoptosis is an important survival strategy for viruses to ensure their own proliferation and survival. Certain viruses express proteins homologous in sequence, structure and function to mammalian pro-survival B-cell lymphoma 2 ...
Marshall, B, Doerflinger, M, Kvansakul, M, Chugh, S, Colman, PM, Caria, S, Puthalakath, H   +6 more
core   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Terminal Region Sequence Variations in Variola Virus DNA

, 1996
Genome DNA terminal region sequences were determined for a Brazilian alastrim variola minor virus strain Garcia-1966 that was associated with an 0.8% case-fatality rate and African smallpox strains Congo-1970 and Somalia-1977 associated with variola ...
KNIGHT, JANICE C., ESPOSITO, JOSEPH J., PARSONS, JOSEPH M., MASSUNG, ROBERT F., SHCHELKUNOV, SERGEI N., GUTOROV, VALERY V., TOTMENIN, ALEXEI V., CHIZHIKOV, VLADIMIR E., SAFRONOV, PAVEL F., LOPAREV, VLADIMIR N.   +9 more
core   +1 more source

In vitro inhibition of monkeypox virus production and spread by Interferon-β

Virology Journal, 2012
Background The Orthopoxvirus genus contains numerous virus species that are capable of causing disease in humans, including variola virus (the etiological agent of smallpox), monkeypox virus, cowpox virus, and vaccinia virus (the prototypical member of ...
Johnston Sara C, Lin Kenny L, Connor John H, Ruthel Gordon, Goff Arthur, Hensley Lisa E   +5 more
doaj   +1 more source

Socioeconomic Risk Factors for Incomplete Vaccination in Swedish Two‐Year‐Olds—A Nationwide, Population‐Based Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim To analyse the association between specific socioeconomic measures and the risk of incomplete vaccination for diphtheria‐tetanus‐pertussis (DTP) and measles‐containing vaccine (MCV) in Swedish two‐year‐olds. Methods This nationwide, population‐based cohort study included 227 457 children born in Sweden during 2014–2015.
Cecilia Chrapkowska Almqvist, Ilias Galanis, Tiia Lepp, Malin Kark, Sharon Kühlmann‐Berenzon, Anna Nilsson   +5 more
wiley   +1 more source

Alastrim Smallpox Variola Minor Virus Genome DNA Sequences

, 2000
Alastrim variola minor virus, which causes mild smallpox, was first recognized in Florida and South America in the late 19th century. Genome linear double-stranded DNA sequences (186,986 bp) of the alastrim virus Garcia-1966, a laboratory reference ...
Chizhikov, Vladimir E., Totmenin, Alexei V., Loparev, Vladimir N., Massung, Robert F., Gutorov, Valery V., Shchelkunov, Sergei N., Safronov, Pavel F., Parsons, Joseph M., Esposito, Joseph J., Knight, Janice C.   +9 more
core   +1 more source

Smallpox lesion characterization in placebo-treated and tecovirimat-treated macaques using traditional and novel methods.

PLoS Pathogens
Smallpox was the most rampant infectious disease killer of the 20th century, yet much remains unknown about the pathogenesis of the variola virus.
Todd M Bell, Paul Facemire, Jeremy J Bearss, Jo Lynne Raymond, Jennifer Chapman, Xiankun Zeng, Joshua D Shamblin, Janice A Williams, Douglas W Grosenbach, Dennis E Hruby, Inger K Damon, Arthur J Goff, Eric M Mucker   +12 more
doaj   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

Cancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan, Ruikang Liu, Fangying Shao, Zheqi Cai, Yingfei Fang, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li   +8 more
wiley   +1 more source