Results 21 to 30 of about 10,893 (204)
HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus. [PDF]
Summary: Histone deacetylases (HDACs) regulate gene expression and innate immunity. Previously, we showed that HDAC5 is degraded during Vaccinia virus (VACV) infection and is a restriction factor for VACV and herpes simplex virus type 1.
Lu Y +6 more
europepmc +2 more sources
Immunofluorescence staining for detection of variola virus [PDF]
In September 1975 Bangladesh was the only country in the world with endemic variola major, and the eradication of the disease was imminent. A rapid and accurate laboratory diagnostic method was required to supplement immunodiffusion in agar gel and culture on chorioallantoic membrane of embryonated egg available at the Institute of Public Health in ...
D J, Tarantola +3 more
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SUSCEPTIBILITY OF SUCKLING MICE TO VARIOLA VIRUS [PDF]
Marshall, Ronald G. (Army Chemical Corps, Fredrick, Md.), and Peter J. Gerone . Susceptibility of suckling mice to variola virus. J. Bacteriol. 82: 15–19. 1961.—The susceptibility of suckling mice inoculated intraperitoneally or intracerebrally with variola virus was investigated.
R G, MARSHALL, P J, GERONE
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Monkeypox Goes North: Ongoing Worldwide Monkeypox Infections in Humans
In the late 1970s, global vaccination programs resulted in the eradication of smallpox. The Monkeypox virus (MPXV), which is closely related to the smallpox-inducing variola virus, was previously endemic only in Sub-Saharan Africa but is currently ...
Barbara S. Schnierle
doaj +1 more source
Flocculation Experiments with Variola and Vaccinia Virus [PDF]
J MMUNOLOGICAL studies of viruses have shown clearly and uniLformly that virucidal properties are developed in the serum of animals following an attack of the disease and in some instances following injection of the killed virus. The demonstration of agglutinins, precipitins or complement-fixing antibodies has not been so convincing and, in contrast to
L C, Havens, C R, Mayfield
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Phylogeographical and evolutionary history of variola major virus; a question of timescales? [PDF]
Aim of this study was to reconstruct the phylogeography of variola virus (VARV) in the XX century, using 47 VARV whole genome sequences available in public databases, through two different methods for ancestral character reconstruction: a frequently used
Bergna, Annalisa +6 more
core +1 more source
Poxviruses are a large and complex family of viruses with members such as monkeypox virus and variola virus. The possibility of an outbreak of monkeypox virus (or a related poxvirus) or the misuse of variola virus justifies the development of ...
Eric M. Mucker +3 more
doaj +1 more source
Use of the Aerosol Rabbitpox Virus Model for Evaluation of Anti-Poxvirus Agents
Smallpox is an acute disease caused by infection with variola virus that has had historic effects on the human population due to its virulence and infectivity.
Thomas G. Voss, Chad J. Roy
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ObjectiveTo examine status quo and development trends of research worldwide on highly pathogenic pathogens. MethodsIn this study, highly pathogenic pathogens refered to 29 pathogens classified as pathogens of first category in the List of Human ...
Luona LI, Kunlan ZUO, Lili MA, Huan LIU
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Diagnóstico laboratorial de varíola: III - resultados do terceiro ano de atividades
Os autores apresentam os resultados obtidos no terceiro ano de atividades do laboratório de Diagnóstico de Varíola, no Instituto Presidente Castello Bran-co, da Fundação Instituto Oswaldo Crus, no Rio de Janeiro.
J. A. Mesquita, H. G. Schatzmayr
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