Results 11 to 20 of about 1,368,656 (159)

A Multiplex PCR/LDR Assay for the Simultaneous Identification of Category A Infectious Pathogens: Agents of Viral Hemorrhagic Fever and Variola Virus. [PDF]

PLoS ONE, 2015
CDC designated category A infectious agents pose a major risk to national security and require special action for public health preparedness. They include viruses that cause viral hemorrhagic fever (VHF) syndrome as well as variola virus, the agent of ...
Sanchita Das, Mark S Rundell, Aashiq H Mirza, Maneesh R Pingle, Kristi Shigyo, Aura R Garrison, Jason Paragas, Scott K Smith, Victoria A Olson, Davise H Larone, Eric D Spitzer, Francis Barany, Linnie M Golightly   +12 more
doaj   +2 more sources

Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido [PDF]

Interdisciplinary Journal of Epidemiology and Public Health, 2022
La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa, Juan Pablo Rojas   +1 more
doaj   +2 more sources

Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?

Emerging Infectious Diseases, 2011
In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
doaj   +2 more sources

Analysis of variola virus molecular evolution suggests an old origin of the virus consistent with historical records. [PDF]

Microb Genom, 2023
Archaeovirology efforts provided a rich portrait of the evolutionary history of variola virus (VARV, the cause of smallpox), which was characterized by lineage extinctions and a relatively recent origin of the virus as a human pathogen (~1700 years ago ...
Forni D, Molteni C, Cagliani R, Clerici M, Sironi M.   +4 more
europepmc   +2 more sources

Neutralization Determinants on Poxviruses

Viruses, 2023
Smallpox was a highly contagious disease caused by the variola virus. The disease affected millions of people over thousands of years and variola virus ranked as one of the deadliest viruses in human history. The complete eradication of smallpox in 1980,
Vernuccio Riccardo, Guardado-Calvo Pablo
doaj   +1 more source

Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]

PLoS ONE, 2015
Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates, Victoria Olson, Scott Smith, Nishi Patel, Inger Damon, Kevin Karem   +5 more
doaj   +1 more source

Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age [PDF]

, 2020
Smallpox, one of the most devastating human diseases, killed between 300 million and 500 million people in the 20th century alone. We recovered viral sequences from 13 northern European individuals, including 11 dated to ~600-1050 CE, overlapping the ...
Moiseyev, Vyacheslav, Smith, GL, Strand, LM, Sikora, Martin, Strand, Lisa Mariann, Holtsmark Nielsen, Sofie, Castro, Constanza De La Fuente, Fouchier, Ron A. M., Allentoft, ME, Jones, Terry C., Muhlemann, B, Smith, Derek, Pushkina, Tamara, Sikora, M, Nielsen, SH, Vinner, Lasse, Drosten, C, Hansen, Anders Johannes, Buzhilova, Alexandra, Østergaard Sørensen, Palle, Moiseyev, V, Smith, Geoffrey L., Magnusson, Y, Fouchier, Ron; id_orcid, Vinner, L, Hansen, Anders J., Magnusson, Yvonne, Sutter, Gerd, Margaryan, A, Smith, Derek J, Fouchier, Ron A M, Falys, Ceri, Fouchier, Ron A.M., Gustin, I, Wilhelmson, H, Khartanovich, V, Jones, Terry C, Buzhilova, A, Schroeder, Hannes, Schroeder, H, Jorkov, MLS, Bill, Jan, Pushkina, T, Willerslev, E, Hansen, AJ, Falys, C, Smith, Geoffrey L, Jones, TC, Nielsen, Sofie Holtsmark, Drosten, Christian, Allentoft, Morten E, Damgaard, PD, Bill, J, de la Fuente Castro, Constanza, Sørensen, Palle Østergaard, Sutter, G, Willerslev, Eske, Castro, CD, de Barros Damgaard, Peter, Khartanovich, Valeri, Sorensen, PO, Mühlemann, Barbara, Wilhelmson, Helene, Gustin, Ingrid, Smith, Derek J., Margaryan, Ashot, Allentoft, Morten E., Damgaard, Peter De Barros, Jørkov, Marie Louise Schjellerup, Strand, Lisa Mariann,, Smith, Derek J.,, Vinner, Lasse,, Jones, Terry C.,, Hansen, Anders Johannes,, Willerslev, Eske,, Østergaard Sørensen, Palle,, Falys, Ceri,, Lund University., Fouchier, Ron A.M.,, Magnusson, Yvonne,, de la Fuente Castro, Constanza,, Schroeder, Hannes,, Bill, Jan,, Smith, Geoffrey L.,, de Barros Damgaard, Peter,, Mühlemann, Barbara,, Khartanovich, Valeri,, Jørkov, Marie Louise Schjellerup,, Sikora, Martin,, Gustin, Ingrid,, Pushkina, Tamara,, Moiseyev, Vyacheslav,, Allentoft, Morten E.,, Wilhelmson, Helene,, Buzhilova, Alexandra,, Margaryan, Ashot,, Holtsmark Nielsen, Sofie,, Sutter, Gerd,, Drosten, Christian,, Tamara Pushkina, Ashot Margaryan, Marie Louise Schjellerup Jørkov, Hannes Schroeder, Ingrid Gustin, Vyacheslav Moiseyev, Peter de Barros Damgaard, Martin Sikora, Lisa Mariann Strand, Sofie Holtsmark Nielsen, Barbara Mühlemann, Jan Bill, Helene Wilhelmson, Ron A. M. Fouchier, Morten E. Allentoft, Geoffrey L. Smith, Derek J. Smith, Ceri Falys, Valeri Khartanovich, Terry C. Jones, Alexandra Buzhilova, Eske Willerslev, Palle Østergaard Sørensen, Constanza de la Fuente Castro, Yvonne Magnusson, Anders Johannes Hansen, Lasse Vinner, Christian Drosten, Gerd Sutter   +127 more
core   +5 more sources

Characterization of Two Historic Smallpox Specimens from a Czech Museum

Viruses, 2017
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer, Jiri Dresler, Hana Kabíckova, Libor Písa, Pavel Aganov, Karel Fucik, Daniel Elleder, Tomas Hron, Vitezslav Kuzelka, Petr Velemínsky, Jana Klimentova, Alena Fucikova, Jaroslav Pejchal, Rita Hrabakova, Vladimir Benes, Tobias Rausch, Pavel Dundr, Alexander Pilin, Radomir Cabala, Martin Hubalek, Jan Stríbrny, Markus H. Antwerpen, Hermann Meyer   +22 more
doaj   +1 more source

Phylogeographical and evolutionary history of variola major virus; a question of timescales? [PDF]

, 2022
Aim of this study was to reconstruct the phylogeography of variola virus (VARV) in the XX century, using 47 VARV whole genome sequences available in public databases, through two different methods for ancestral character reconstruction: a frequently used
Bergna, Annalisa, Ciccozzi, Massimo, Marzo, Rossella, Lai, Alessia, Galli, Massimo, Zehender, Gianguglielmo, Ventura, Carla Della   +6 more
core   +1 more source

Functional epitopes and neutralizing antibodies of vaccinia virus

Frontiers in Microbiology, 2023
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng, Naijing Hu, Yingjun Liu, Cong Xing, Longlong Luo, Xinying Li, Jing Wang, Guojiang Chen, He Xiao, Chenghua Liu, Beifen Shen, Jiannan Feng, Chunxia Qiao   +12 more
doaj   +1 more source