Results 11 to 20 of about 10,893 (204)
Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?
Emerging Infectious Diseases, 2011 In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
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In Silico Studies of Potential Selective Inhibitors of Thymidylate Kinase from Variola virus. [PDF]
Pharmaceuticals (Basel), 2021 Continuing the work developed by our research group, in the present manuscript, we performed a theoretical study of 10 new structures derived from the antivirals cidofovir and ribavirin, as inhibitor prototypes for the enzyme thymidylate kinase from ...
Garcia DR +7 more
europepmc +2 more sources
A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review. [PDF]
Health Sci RepABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Aqeel MB +6 more
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17th Century Variola Virus Reveals the Recent History of Smallpox. [PDF]
Curr Biol, 2016 Smallpox holds a unique position in the history of medicine. It was the first disease for which a vaccine was developed and remains the only human disease eradicated by vaccination.
Duggan AT +20 more
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Neutralization Determinants on Poxviruses
Viruses, 2023 Smallpox was a highly contagious disease caused by the variola virus. The disease affected millions of people over thousands of years and variola virus ranked as one of the deadliest viruses in human history. The complete eradication of smallpox in 1980,
Vernuccio Riccardo, Guardado-Calvo Pablo
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Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]
PLoS ONE, 2015 Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates +5 more
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Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido
Interdisciplinary Journal of Epidemiology and Public Health, 2022 La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa +1 more
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Functional epitopes and neutralizing antibodies of vaccinia virus
Frontiers in Microbiology, 2023 Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng +12 more
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mSphere, 2021 Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson +14 more
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Characterization of Two Historic Smallpox Specimens from a Czech Museum
Viruses, 2017 Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer +22 more
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