Results 11 to 20 of about 1,046,980 (206)

Evidence of Long-Distance Aerial Convection of Variola Virus and Implications for Disease Control [PDF]

Viruses, 2019
Two distinct phenomena of airborne transmission of variola virus (smallpox) were described in the pre-eradication era—direct respiratory transmission, and a unique phenomenon of transmission over greater distances, referred to as “aerial ...
Chandini Raina MacIntyre, Arpita Das, Xin Chen, Charitha De Silva, Con Doolan   +4 more
doaj   +4 more sources

EPIPOX: Immunoinformatic Characterization of the Shared T-Cell Epitome between Variola Virus and Related Pathogenic Orthopoxviruses [PDF]

Journal of Immunology Research, 2015
Concerns that variola viruses might be used as bioweapons have renewed the interest in developing new and safer smallpox vaccines. Variola virus genomes are now widely available, allowing computational characterization of the entire T-cell epitome and ...
Magdalena Molero-Abraham, John-Paul Glutting, Darren R. Flower, Esther M. Lafuente, Pedro A. Reche   +4 more
doaj   +4 more sources

17$^{th}$ Century Variola Virus Reveals the Recent History of Smallpox [PDF]

Curr Biol, 2016
Smallpox holds a unique position in the history of medicine. It was the first disease for which a vaccine was developed and remains the only human disease eradicated by vaccination.
Duchene, Sebastian, Sahl, Jason W., Marciniak, Stephanie,, Marciniak, Stephanie, Emery, Matthew V., Dutour, Olivier, Southon, John, Hedman, Klaus, Poinar, Hendrik N.,, Sahl, Jason W.,, Holmes, Edward C.,, Golding, G. Brian,, Poinar, Debi, Poinar, Debi,, Devault, Alison,, Poinar, Hendrik N., Duggan, Ana T., Smith, Geoffrey L., Sajantila, Antti,, Southon, John,, Perdomo, Maria F.,, Jankauskas, Rimantas, Piombino Mascali, Dario,, Piombino-Mascali, Dario, Buchmann, Jan P., Perdomo , Maria F., Humphreys, Margaret, Holmes, Edward C., Jankauskas, Rimantas,, Sajantila, Antti, Duggan, Ana T.,, Devault, Alison, Golding, G. Brian, Humphreys, Margaret,, Buchmann, Jan P.,, Dutour, Olivier,, Smith, Geoffrey L.,, Rouillard, Jean-Marie,, Emery, Matthew,, Duchene, Sebastian,, Hedman, Klaus,, Rouillard, Jean-Marie   +41 more
core   +5 more sources

Identification of SNPs associated with variola virus virulence [PDF]

BioData Mining, 2013
Abstract Background Decades after the eradication of smallpox, its etiological agent, variola virus (VARV), remains a threat as a potential bioweapon. Outbreaks of smallpox around the time of the global eradication effort exhibited variable case fatality rates (CFRs), likely attributable in part to complex viral ...
Anne Gatewood Hoen, Shea N. Gardner, Jason H. Moore   +2 more
openaire   +4 more sources

Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?

Emerging Infectious Diseases, 2011
In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
doaj   +2 more sources

Efficacy of heat against the vaccinia virus, variola virus and monkeypox virus [PDF]

Journal of Hospital Infection, 2022
Kampf G.
openaire   +3 more sources

Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age [PDF]

, 2020
Smallpox, one of the most devastating human diseases, killed between 300 million and 500 million people in the 20th century alone. We recovered viral sequences from 13 northern European individuals, including 11 dated to ~600-1050 CE, overlapping the ...
Moiseyev, Vyacheslav, Smith, GL, Strand, LM, Sikora, Martin, Strand, Lisa Mariann, Holtsmark Nielsen, Sofie, Castro, Constanza De La Fuente, Fouchier, Ron A. M., Allentoft, ME, Jones, Terry C., Muhlemann, B, Smith, Derek, Pushkina, Tamara, Sikora, M, Nielsen, SH, Vinner, Lasse, Drosten, C, Hansen, Anders Johannes, Buzhilova, Alexandra, Østergaard Sørensen, Palle, Moiseyev, V, Smith, Geoffrey L., Magnusson, Y, Fouchier, Ron; id_orcid, Vinner, L, Hansen, Anders J., Magnusson, Yvonne, Sutter, Gerd, Margaryan, A, Smith, Derek J, Fouchier, Ron A M, Falys, Ceri, Fouchier, Ron A.M., Gustin, I, Wilhelmson, H, Khartanovich, V, Jones, Terry C, Buzhilova, A, Schroeder, Hannes, Schroeder, H, Jorkov, MLS, Bill, Jan, Pushkina, T, Willerslev, E, Hansen, AJ, Falys, C, Smith, Geoffrey L, Jones, TC, Nielsen, Sofie Holtsmark, Drosten, Christian, Allentoft, Morten E, Damgaard, PD, Bill, J, de la Fuente Castro, Constanza, Sørensen, Palle Østergaard, Sutter, G, Willerslev, Eske, Castro, CD, de Barros Damgaard, Peter, Khartanovich, Valeri, Sorensen, PO, Mühlemann, Barbara, Fouchier, Ron, Wilhelmson, Helene, Gustin, Ingrid, Smith, Derek J., Margaryan, Ashot, Allentoft, Morten E., Damgaard, Peter De Barros, Jørkov, Marie Louise Schjellerup   +69 more
core   +5 more sources

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

mSphere, 2021
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson, Ashley V. Kondas, Mathew R. Mauldin, Jeffrey B. Doty, Irma M. Grossi, Clint N. Morgan, Sharon Dietz Ostergaard, Christine M. Hughes, Yoshinori Nakazawa, Chantal Kling, Brock E. Martin, James A. Ellison, Darin D. Carroll, Nadia F. Gallardo-Romero, Victoria A. Olson   +14 more
doaj   +1 more source

Characterization of Two Historic Smallpox Specimens from a Czech Museum

Viruses, 2017
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer, Jiri Dresler, Hana Kabíckova, Libor Písa, Pavel Aganov, Karel Fucik, Daniel Elleder, Tomas Hron, Vitezslav Kuzelka, Petr Velemínsky, Jana Klimentova, Alena Fucikova, Jaroslav Pejchal, Rita Hrabakova, Vladimir Benes, Tobias Rausch, Pavel Dundr, Alexander Pilin, Radomir Cabala, Martin Hubalek, Jan Stríbrny, Markus H. Antwerpen, Hermann Meyer   +22 more
doaj   +1 more source

Immunofluorescence staining for detection of variola virus [PDF]

Journal of Clinical Microbiology, 1981
In September 1975 Bangladesh was the only country in the world with endemic variola major, and the eradication of the disease was imminent. A rapid and accurate laboratory diagnostic method was required to supplement immunodiffusion in agar gel and culture on chorioallantoic membrane of embryonated egg available at the Institute of Public Health in ...
D J, Tarantola, F, Huq, J H, Nakano, S O, Foster   +3 more
openaire   +2 more sources