HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus [PDF]
Cell ReportsGeoffrey L Smith, Lu Yongxu
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Neutralization Determinants on Poxviruses
Viruses, 2023 Smallpox was a highly contagious disease caused by the variola virus. The disease affected millions of people over thousands of years and variola virus ranked as one of the deadliest viruses in human history. The complete eradication of smallpox in 1980,
Vernuccio Riccardo, Guardado-Calvo Pablo
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Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]
PLoS ONE, 2015 Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates +5 more
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A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review. [PDF]
Health Sci RepABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Aqeel MB +6 more
europepmc +2 more sources
Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido
Interdisciplinary Journal of Epidemiology and Public Health, 2022 La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa +1 more
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Functional epitopes and neutralizing antibodies of vaccinia virus
Frontiers in Microbiology, 2023 Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng +12 more
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mSphere, 2021 Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson +14 more
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Flocculation Experiments with Variola and Vaccinia Virus [PDF]
American Journal of Public Health and the Nations Health, 1931 J MMUNOLOGICAL studies of viruses have shown clearly and uniLformly that virucidal properties are developed in the serum of animals following an attack of the disease and in some instances following injection of the killed virus. The demonstration of agglutinins, precipitins or complement-fixing antibodies has not been so convincing and, in contrast to
L C, Havens, C R, Mayfield
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Characterization of Two Historic Smallpox Specimens from a Czech Museum
Viruses, 2017 Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer +22 more
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SUSCEPTIBILITY OF SUCKLING MICE TO VARIOLA VIRUS [PDF]
Journal of Bacteriology, 1961 Marshall, Ronald G. (Army Chemical Corps, Fredrick, Md.), and Peter J. Gerone . Susceptibility of suckling mice to variola virus. J. Bacteriol. 82: 15–19. 1961.—The susceptibility of suckling mice inoculated intraperitoneally or intracerebrally with variola virus was investigated.
R G, MARSHALL, P J, GERONE
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