Results 21 to 30 of about 443,542 (283)

Reversal of aging-induced increases in aortic stiffness by targeting cytoskeletal protein-protein interfaces [PDF]

, 2018
Background: The proximal aorta normally functions as a critical shock absorber that protects small downstream vessels from damage by pressure and flow pulsatility generated by the heart during systole.
AortaGen Consortium, the, Bekaert, Sofie, Chiu, Joanna G, De Backer, Gui, De Bacquer, Dirk, De Buyzere, Marc, De Meyer, Tim, Gao, Yuan Z, Gillebert, Thierry, Leavis, Paul, Li, Qian, Mitchell, GF, Morgan, Kathleen G, Nicholson, Christopher J, Porter, Tyrone, Rietzschel, Ernst, Saphirstein, Robert J, Segers, Patrick, Singh, Kuldeep, Van Bortel, Lucas, Verwoert, Germaine C   +20 more
core   +5 more sources

Bleomycin increases neutrophil adhesion to human vascular endothelial cells independently of upregulation of ICAM-1 and E-selectin [PDF]

, 2016
© 2016 Taylor & Francis. Aim of the Study: Bleomycin-induced lung disease is a serious complication of therapy characterized by alveolar injury, cytokine release, inflammatory cell recruitment, and eventually pulmonary fibrosis.
Crooks, Michael G., Greenman, John, Hart, Simon P., Sadofsky, Laura R., Williamson, James D.   +4 more
core   +1 more source

Gender and age peculiarities of content changes of protein C, von Willebrand factor, vascular cell adhesion molecules sVCAM-1 in patients with acute left ventricle Q-wave myocardial infarction

Zaporožskij Medicinskij Žurnal, 2015
Markers of hemostasis have an influence on the state of postinfarction remodeling processes. Aim. In order to study the gender and age peculiarities, to determine the predictive value of the protein C, von Willebrand factor and vascular cell adhesion ...
S. M. Kyselov
doaj   +1 more source

Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression. [PDF]

, 2012
Vascular cell adhesion molecule-1 (VCAM-1) plays important roles in development and inflammation. Tumor necrosis factor-α (TNF-α) and focal adhesion kinase (FAK) are key regulators of inflammatory and integrin-matrix signaling, respectively.
Chen, Xiao Lei, Cheresh, David A, Lawson, Christine, Lim, Ssang-Taek, Miller, Nichol LG, Schlaepfer, David D, Tancioni, Isabelle, Uryu, Sean, Walsh, Colin T, Weis, Sara M   +9 more
core   +1 more source

Human Vascular Adhesion Protein-1 in Smooth Muscle Cells [PDF]

The American Journal of Pathology, 1999
Human vascular adhesion protein-1 (VAP-1) is a dual-function molecule with adhesive and enzymatic properties. In addition to synthesis in endothelial cells, where it mediates lymphocyte binding, VAP-1 is expressed in smooth muscle cells. Here we studied the expression, biochemical structure, and function of VAP-1 in muscle cells and compared it to ...
K, Jaakkola, K, Kaunismäki, S, Tohka, G, Yegutkin, E, Vänttinen, T, Havia, L J, Pelliniemi, M, Virolainen, S, Jalkanen, M, Salmi   +9 more
openaire   +2 more sources

Vascular Adhesion Protein 1 Mediates Gut Microbial Flagellin-Induced Inflammation, Leukocyte Infiltration, and Hepatic Steatosis

Sci, 2021
Toll-like receptor 5 ligand, flagellin, and vascular adhesion protein 1 (VAP-1) are involved in non-alcoholic fatty liver disease. This study aimed to determine whether VAP-1 mediates flagellin-induced hepatic fat accumulation.
Raine Toivonen, Sanja Vanhatalo, Maija Hollmén, Eveliina Munukka, Anniina Keskitalo, Sami Pietilä, Laura Elo, Pentti Huovinen, Sirpa Jalkanen, Satu Pekkala   +9 more
doaj   +1 more source

Vascular Adhesion Protein-1: A Cell Surface Amine Oxidase in Translation. [PDF]

Antioxid Redox Signal, 2019
Significance: Vascular adhesion protein-1 (VAP-1) is an ectoenzyme that oxidates primary amines in a reaction producing also hydrogen peroxide. VAP-1 on the blood vessel endothelium regulates leukocyte extravasation from the blood into tissues under physiological and pathological conditions.
Salmi M, Jalkanen S.
europepmc   +4 more sources

Vascular adhesion protein 1 in nonalcoholic steatohepatitis: a novel biomarker? [PDF]

Hepatology, 2015
Torok NJ.
europepmc   +4 more sources

Platelets at the vascular interface [PDF]

, 2018
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Bergmeier, Wolfgang, Stefanini, Lucia
core   +1 more source

Clinical study of adjuvant therapy on ischemic stroke with salviae miltiorrhizae and ligustrazine

Journal of Acute Disease, 2017
Objective: To study the effect of adjuvant therapy with salviae miltiorrhizae and ligustrazine injection on neural function injury, degree of oxidative stress reaction, chemotactic factor and adhesion molecule in patients with ischemic stroke.
Jing-Qin Tian, Wei Zhang
doaj   +1 more source