Results 51 to 60 of about 444,049 (319)

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

open access: yes, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT   +28 more
core   +1 more source

Inhibitory Effect of Indigo Naturalis on Tumor Necrosis Factor-α-Induced Vascular Cell Adhesion Molecule-1 Expression in Human Umbilical Vein Endothelial Cells

open access: yesMolecules, 2010
The use of indigo naturalis to treat psoriasis has proved effective in our previous clinical studies. The present study was designed to examine the anti-inflammatory effect of indigo naturalis in primary cultured human umbilical vein endothelial cells ...
Hsin-Ning Chang   +6 more
doaj   +1 more source

Dependence of endothelial cell growth on substrate-bound fibronectin [PDF]

open access: yes, 1992
A better understanding of the mechanism of adhesion, spreading and proliferation of human endothelial cells (HEC) on polymeric surfaces may lead to the development of vascular prostheses which allow the formation of an endothelial lining on the luminal ...
Aken, W.G. van   +7 more
core   +2 more sources

Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction [PDF]

open access: yes, 2015
Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase
Cantatore, S   +6 more
core   +1 more source

Elongated membrane tethers, individually anchored by high affinity α4β1/VCAM-1 complexes, are the quantal units of monocyte arrests. [PDF]

open access: yesPLoS ONE, 2013
The α4β1 integrin facilitates both monocyte rolling and adhesion to the vascular endothelium and is physiologically activated by monocyte chemoattractant protein (MCP-1). The current study investigated the initial events in the adhesion of THP-1 cells to
Calvin Chu   +3 more
doaj   +1 more source

Atorvastatin suppresses lipopolysaccharide-induced inflammation in human coronary artery endothelial cells

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2022
The present study was designed to examine the effects of atorvastatin on vascular inflammatory responses in human coronary artery endothelial cells(HCAECs), when challenged by lipopolysaccharide (LPS), a Toll-like receptor-4 (TLR4) ligand.
Zhen Tian   +4 more
doaj   +1 more source

Vascular Adhesion Protein-1 Mediates Adhesion and Transmigration of Lymphocytes on Human Hepatic Endothelial Cells [PDF]

open access: yesThe Journal of Immunology, 2001
Abstract Vascular adhesion protein-1 (VAP-1) is an amine oxidase and adhesion receptor that is expressed by endothelium in the human liver. The hepatic sinusoids are perfused by blood at low flow rates, and sinusoidal endothelium lacks selectin expression and has low levels of CD31, suggesting that VAP-1 may play a specific role in ...
Patricia F, Lalor   +5 more
openaire   +2 more sources

Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction

open access: yesScientific Reports, 2021
Stroke is a multiphasic process involving a direct ischemic brain injury which is then exacerbated by the influx of immune cells into the brain tissue. Activation of brain endothelial cells leads to the expression of adhesion molecules such vascular cell
Lori N. Eidson   +12 more
doaj   +1 more source

VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]

open access: yes, 2003
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP   +14 more
core   +1 more source

Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy

open access: yesJournal of Ophthalmology, 2015
Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. The objective of this study is to investigate the effects of vascular endothelial growth factor receptor 1 (VEGFR1) blockade on the complications of DR.
Jianbo He   +5 more
doaj   +1 more source

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