Results 111 to 120 of about 1,468,943 (359)

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

open access: yesAdvanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv   +10 more
wiley   +1 more source

Multifaceted Mechanisms of Vascular Calcification in Aging.

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2019
Approximately 20% of the world's population will be around or above 65 years of age by the next decade. Out of these, 40% are suspected to have cardiovascular diseases as a cause of mortality.
Luciana A. Pescatore   +2 more
semanticscholar   +1 more source

Bioinspired Bromination Enables Extensible, Strain‐Stiffening Resilin Peptide Scaffolds with Tunable Degradation

open access: yesAdvanced Functional Materials, EarlyView.
Bioinspired bromination of a resilin‐derived peptide enables the fabrication of electrospun nanofibrous scaffolds that uniquely combine strain‐stiffening elasticity, proteolytic stability, and antioxidant functionality. These brominated peptide–gelatin hybrids mimic the extensibility of natural elastomers, demonstrating tunable mechanical resilience ...
Elisa Marelli   +6 more
wiley   +1 more source

The Relationship of Osteoprotegerin, Matrix Gla Protein, and HbA1C in Controlled and Uncontrolled Type 2 Diabetes Mellitus Patients

open access: yesIndonesian Biomedical Journal, 2010
BACKGROUND: Many studies have reported that diabetes mellitus correlates with vascular calcification event that increases progressively in uncontrolled diabetes.
Dwi Yuniati Daulay   +2 more
doaj   +1 more source

Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

open access: yesNature Communications, 2019
Vascular calcification is highly prevalent in end-stage renal diseases and is predictive of cardiovascular events and mortality. Poly(ADP-ribose) polymerase 1 (PARP1) inhibition or deletion is vasoprotective in several disease models.
Cheng Wang   +7 more
semanticscholar   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

Extensive vascular calcification

open access: yesIndian Journal of Health Sciences and Biomedical Research (KLEU), 2015
Calciphylaxis denotes the presence of cutaneous gangrene secondary to the ischemic necrosis caused by vascular calcification. This is seen in patients with end stage renal disease, especially those using the renal replacement therapy. We recently encountered an elderly patient with long standing type 2 diabetes who presented with diabetic foot disease.
Mukesh Dhillon   +3 more
openaire   +2 more sources

The interplay between mineral metabolism, vascular calcification and inflammation in Chronic Kidney Disease (CKD): challenging old concepts with new facts

open access: yesAging, 2019
Chronic kidney disease (CKD) is one of the most powerful predictors of premature cardiovascular disease (CVD), with heightened susceptibility to vascular intimal and medial calcification associated with a high cardiovascular mortality.
C. Viegas   +3 more
semanticscholar   +1 more source

Endothelial Cells Angiogenesis in Sulfated Glycosaminoglycan (GAG) Hydrogels Enhanced by Bioactive Glass‐Released Ions

open access: yesAdvanced Functional Materials, EarlyView.
A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni   +13 more
wiley   +1 more source

Proinflammatory Vascular Calcification [PDF]

open access: yesCirculation Research, 2005
See related article, pages 1248–1256 Vascular calcification occurs as part of atherosclerosis. It is caused by the deposition of basic calcium phosphate (BCP) crystals in what appears to be a highly regulated process resembling bone formation.1–4 Vascular calcification occurs in several forms,1–4 including small crystal deposits in the neointima ...
openaire   +1 more source

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