Results 151 to 160 of about 1,499,832 (396)

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Significant Association Between Bone-Specific Alkaline Phosphatase and Vascular Calcification of the Hand Arteries in Male Hemodialysis Patients

Kidney & Blood Pressure Research, 2014
Background/Aims: Bone-specific alkaline phosphatase (BAP) hydrolyzes pyrophosphate, which inhibits vascular calcification. We examined association between serum BAP and vascular calcification of male hemodialysis patients.
Eiji Ishimura, Senji Okuno, Hisanori Okazaki, Kyoko Norimine, Kenjiro Yamakawa, Tomoyuki Yamakawa, Shigeichi Shoji, Yoshiki Nishizawa, Masaaki Inaba   +8 more
doaj   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

Coronary age, based on coronary calcium measurement, is increased in patients with morbid obesity [PDF]

, 2018
Purpose: Obesity is a well-known of risk factor for atherosclerosis. However, recently an "obesity paradox" has been discussed, which is considered as a protective effect of obesity on the development coronary artery disease (CAD).
Białecki, Marcin, Hawrył, Mateusz, Lemanowicz, Adam, Leszczyński, Waldemar   +3 more
core   +1 more source

Vascular wall microenvironment: Endothelial cells original exosomes mediated melatonin-suppressed vascular calcification and vascular ageing in a m6A methylation dependent manner

Bioactive Materials
Vascular calcification and vascular ageing are “silent” diseases but are highly prevalent in patients with end stage renal failure and type 2 diabetes, as well as in the ageing population. Melatonin (MT) has been shown to induce cardiovascular protection
Su-Kang Shan, Xiao Lin, Feng Wu, Chang-Chun Li, Bei Guo, Fu-Xing-Zi Li, Ming-Hui Zheng, Yi Wang, Qiu-Shuang Xu, Li-Min Lei, Ke-Xin Tang, Yun-Yun Wu, Jia-Yue Duan, Ye-Chi Cao, Yan-Lin Wu, Chang-Ming Tan, Zi-Han Liu, Zhi-Ang Zhou, Xiao-Bo Liao, Feng Xu, Ling-Qing Yuan   +20 more
doaj   +1 more source

Bicontinuous Microarchitected Scaffolds Provide Topographic Cues That Govern Neuronal Behavior and Maturation

Advanced Functional Materials, EarlyView.
A scalable biomimetic platform transforms bioinert poly(ethylene glycol) diacrylate into neuroinstructive matrices via integrating solvent transfer‐induced phase separation, microfluidics, and 3D bioprinting. Bicontinuous, hyperbolically curved microporous networks embedded within a fibrous construct elicit rapid adhesion, robust proliferation, and ...
Prince D. Okoro, Kevin Dalsania, Shiril B. Iragavarapu, Benjamin Dela Cruz, Aihik Banerjee, Merve Basaranbilek, Martin F. Haase, Bahman Anvari, Iman Noshadi   +8 more
wiley   +1 more source

Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2

Journal of Pathology, 2019
Endothelial‐to‐mesenchymal transition (EndMT) has been unveiled as a common cause for a multitude of human pathologies, including cancer and cardiovascular disease.
G. Sánchez-Duffhues, A. García de Vinuesa, V. van de Pol, M. Geerts, M. D. de Vries, Stef G. Janson, H. van Dam, J. Lindeman, M. Goumans, P. ten Dijke   +9 more
semanticscholar   +1 more source

Unlock the Walnut: How a Pectin‐Rich Suture Tissue and Moisture‐Driven Crack Formation Induce Shell Splitting and Facilitate Seed Germination

Advanced Functional Materials, EarlyView.
Walnut seeds are enclosed in a remarkably strong shell made of sclerenchyma, separated by a pectin‐rich suture tissue. Different cell shapes and chemical composition of this tissue point to an opening mechanism, which is triggered by cyclic humidity changes.
Sebastian J. Antreich, Nannan Xiao, Martin Felhofer, Notburga Gierlinger   +3 more
wiley   +1 more source

Quantitative analysis of vascular calcification

Experimental and Therapeutic Medicine, 2013
Vascular calcification is a prominent feature of atherosclerosis. The mineral composition and quantity within calcified arterial plaques remains unelucidated; therefore, the aim of this study was to analyze the mineral composition of such plaques. Calcified arterial plaques were obtained from patients with abdominal aortic aneurysms (AAAs) and carotid ...
Dong-Ik Kim, Jin Hyun Joh
openaire   +3 more sources

Nanoparticles Decorated Nanotubes: Advanced Local Therapies From Anodized Nanoengineered Titanium Implants

Advanced Functional Materials, EarlyView.
This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra, Liwen Zhang, Tianqi Guo, Sašo Ivanovski, Ruirui Qiao, Karan Gulati   +5 more
wiley   +1 more source