Results 161 to 170 of about 1,474,592 (383)
Effect of gallic acid on Alkaline phosphatase gene expression in vascular smooth muscle cells [PDF]
Background and purpose: Vascular calcification is an important factor in pathogenesis of atherosclerosis. Studies have shown that alkaline phosphatase increases vascular calcification.
Farrokhi, E.+4 more
core
The living aortic valve: From molecules to function. [PDF]
The aortic valve lies in a unique hemodynamic environment, one characterized by a range of stresses (shear stress, bending forces, loading forces and strain) that vary in intensity and direction throughout the cardiac cycle.
Bertazzo, S+5 more
core +1 more source
The Key Role of Phosphate on Vascular Calcification
Vascular calcification (VC) is common in dialysis and non-dialysis chronic kidney disease (CKD) patients, even in the early stage of the disease. For this reason, it can be considered a CKD hallmark.
M. Cozzolino+6 more
semanticscholar +1 more source
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu+7 more
wiley +1 more source
Atmospheric PM2.5 exposure greatly contributes to the incidence of and mortality from cardiovascular disease (CVD). Owing to the crucial role of vascular calcification in the progression of CVD, it is imperative to elucidate the effects of PM2.5 on ...
Ruijun Su+5 more
doaj
Cutaneous Gangrene, Vascular Calcification, and Hyperparathyroidism [PDF]
David A. Mehregan, R.K. Winkelmann
openalex +1 more source
Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2
Vascular calcification is highly prevalent in end-stage renal diseases and is predictive of cardiovascular events and mortality. Poly(ADP-ribose) polymerase 1 (PARP1) inhibition or deletion is vasoprotective in several disease models.
Cheng Wang+7 more
semanticscholar +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1asj mice, a model for generalized arterial calcification of infancy. [PDF]
Generalized arterial calcification of infancy (GACI) is an autosomal recessive disorder caused by mutations in the ENPP1 gene. It is characterized by mineralization of the arterial blood vessels, often diagnosed prenatally, and associated with death in ...
Kingman, Joshua+2 more
core +1 more source
Walnut seeds are enclosed in a remarkably strong shell made of sclerenchyma, separated by a pectin‐rich suture tissue. Different cell shapes and chemical composition of this tissue point to an opening mechanism, which is triggered by cyclic humidity changes.
Sebastian J. Antreich+3 more
wiley +1 more source