Results 171 to 180 of about 1,468,943 (359)

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

PDZ domain containing protein 1 aggravates mouse vascular smooth muscle cells calcification via PDZ1 domain mediated β-catenin stabilization and nuclear translocation

Communications Biology
Vascular calcification is tightly associated with cardiometabolic risk events. PDZK1 (PDZ domain containing 1) has been implicated in protecting from atherosclerosis, however, its relationship with vascular calcification remains unclear.
Changyan Li, Ping Yang, Xiang Liu, Xingyu Chen, Song Mei, Lin Yang, Gaosheng Yin, Shuangxiu Li, Jun Tao, Limei Li, Nan Wu, Lin Sun   +11 more
doaj   +1 more source

Assessment of Arterial Stiffening and Vascular Calcifications in End‐Stage Renal Disease Patients

, 2017
Mahmoud Elsamman, Mohamed Abdel Wahab Ezzat, Medhat Ibraheem Mohammad, Raghda Gamal Mostafa, Ali Hassan   +4 more
openalex   +2 more sources

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Role of Local Versus Systemic Vitamin D Receptors in Vascular Calcification [PDF]

, 2013
Koba A. Lomashvili, Xiaonan Wang, W. Charles O’Neill   +2 more
openalex   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Association between Vascular Calcification, Atherosclerosis and Inflammatory Markers in End-stage Renal Disease Patient

, 2023
Rüya Mutluay, Çiğdem Mengüş, Neslihan Tezcan, Emel İşiktaş Sayilar, Ülver Derici, Ceyla Konca Değertekin, Serap Gültekin, Sevim Gönen, Gülten Taçoy   +8 more
openalex   +2 more sources

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Vascular calcification in patients with type 2 diabetes: the involvement of matrix Gla protein [PDF]

, 2014
Sophie Liabeuf, Olivier Bourron, Cees Vemeer, Elke Theuwissen, Elke Magdeleyns, Carole E. Aubert, Michel Brazier, Romuald Mentaverri, Agnès Hartemann, Ziad A. Massy   +9 more
openalex   +1 more source