Results 221 to 230 of about 93,447 (262)
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Current Opinion in Nephrology & Hypertension, 2013
This review presents new evidence related to molecular mechanisms involved in the process of cardiovascular calcification, as well as to discuss new biomarkers and novel therapeutic strategies related to vascular calcification in chronic kidney disease (CKD) patients.microRNAs have emerged as potential players in the genesis of osteo-chondrogenic ...
Ziad A, Massy, Tilman B, Drüeke
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This review presents new evidence related to molecular mechanisms involved in the process of cardiovascular calcification, as well as to discuss new biomarkers and novel therapeutic strategies related to vascular calcification in chronic kidney disease (CKD) patients.microRNAs have emerged as potential players in the genesis of osteo-chondrogenic ...
Ziad A, Massy, Tilman B, Drüeke
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Pathophysiology of Vascular Calcification
Current Osteoporosis Reports, 2015Vascular calcification can lead to cardiovascular morbidity and mortality. The initiating factors and clinical consequences depend on the underlying disease state and location of the calcification. The pathogenesis of vascular calcification is complex and involves a transformation of vascular smooth muscle cells to an osteo/chondrocytic cell that ...
Sharon Moe, Neal Chen, Moe Sharon M
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Current Opinion in Nephrology and Hypertension, 1999
Vascular calcification is an active and modifiable process involved in many disease entities, including atherosclerosis, cardiac valve disease and calcific uremic arteriolopathy. It occurs with distinct characteristics at different sites in the vessel wall.
R C, Christian, L A, Fitzpatrick
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Vascular calcification is an active and modifiable process involved in many disease entities, including atherosclerosis, cardiac valve disease and calcific uremic arteriolopathy. It occurs with distinct characteristics at different sites in the vessel wall.
R C, Christian, L A, Fitzpatrick
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Inflammation and Vascular Calcification
Blood Purification, 2005Both vascular calcification and inflammation are common in patients with chronic kidney disease (CKD). In patients on dialysis, there is increased coronary artery and peripheral artery calcification compared to the general population. Both intimal (atherosclerotic) and medial calcification in CKD patients are associated with increased morbidity and ...
Sharon M, Moe, Neal X, Chen
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Imaging for Vascular Calcification
Seminars in Dialysis, 2017AbstractChronic decline in renal function is accompanied by deterioration of bone structure and function and progressive calcification of the vascular system. Both disease states have been linked with increased morbidity and mortality in chronic kidney disease.
Paolo, Raggi, W Charles, O'Neill
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The biology of vascular calcification
2020Vascular calcification (VC), characterized by different mineral deposits (i.e., carbonate apatite, whitlockite and hydroxyapatite) accumulating in blood vessels and valves, represents a relevant pathological process for the aging population and a life-threatening complication in acquired and in genetic diseases.
Quaglino D., Boraldi F., Lofaro F. D.
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Warfarin and Vascular Calcification
The American Journal of Medicine, 2016The vitamin K antagonist, warfarin, is the most commonly prescribed oral anticoagulant. Use of warfarin is associated with an increase in systemic calcification, including in the coronary and peripheral vasculature. This increase in vascular calcification is due to inhibition of the enzyme matrix gamma-carboxyglutamate Gla protein (MGP).
Timothy J, Poterucha +1 more
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Current Opinion in Nephrology & Hypertension, 2005
Accumulating evidence suggests that the high cardiovascular mortality observed in patients with end-stage renal disease is due in part to the deleterious effects of vascular calcification that develops over time on dialysis. This review focuses on recent cell biological and animal studies that have shed light on the mechanisms and regulators of ...
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Accumulating evidence suggests that the high cardiovascular mortality observed in patients with end-stage renal disease is due in part to the deleterious effects of vascular calcification that develops over time on dialysis. This review focuses on recent cell biological and animal studies that have shed light on the mechanisms and regulators of ...
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Vascular calcification in dermatopathology
The American Journal of Dermatopathology, 1979Calcification in cutaneous blood vessels is an uncommon finding in biopsies submitted for dermatopathological examination. Of 14 biopsy specimens showing the phenomenon that was studied by us, the greater number was from women who had a combination of severe diabetes, hypertension, and atherosclerosis.
S, Kossard, R K, Winkelmann
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Mechanisms of Vascular Calcification
Advances in Chronic Kidney Disease, 2007Vascular calcification is highly prevalent and correlated with high rates of cardiovascular mortality in chronic kidney disease patients. Recent evidence suggests that mineral, hormonal, and metabolic imbalances that promote phenotype change in vascular cells as well as deficiencies in specific mineralization inhibitory pathways may be important ...
Mohga, El-Abbadi, Cecilia M, Giachelli
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