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Vascular Calcification

2002
Vascular calcification is a pathological calcification process. Its pathogenesis involves active mineralization by chondrogenic and osteogenic cells. Since cartilaginous metaplasia has been found in several vascular diseases, this process may represent one of vascular remodeling in response to vascular injury.
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Preventing vascular calcification

Science, 2016
Vascular Disease The arterial calcification that develops in patients with the genetic disease ACDC (arterial calcification due to deficiency of CD73) leads to peripheral ischemia. Cells from these patients have increased levels of an enzyme that degrades pyrophosphate, a compound that inhibits calcification. Jin et al.
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Vascular calcification and bone disease: the calcification paradox

Trends in Molecular Medicine, 2009
Vascular calcification or ectopic mineralization in blood vessels is an active, cell-regulated process, increasingly recognized as a general cardiovascular risk factor. Remarkably, ectopic artery mineralization is frequently accompanied by decreased bone mineral density or disturbed bone turnover.
Persy, Veerle, d' Haese, Patrick C.
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Hypertension and vascular calcification

Journal of Hypertension, 2012
It is now well established that hypertension is accompanied by remodeling of the arterial wall with significant modifications in extracellular matrix composition and in vascular cell phenotype. Some of these changes, particularly elastin fragments generation, increased proteases activity and activation of transforming growth factor-β signaling together
RATTAZZI, MARCELLO   +4 more
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The role of osteoprogenitors in vascular calcification

Current Opinion in Nephrology and Hypertension, 2000
Calcification is a component of vascular disease that usually occurs in concert with atheroma formation but through distinct pathophysiological processes. Vessel wall osteoprogenitor cells known as calcifying vascular cells can form bone matrix proteins and calcified nodules, analogous to osteoblastic differentiation in bone.
M G, Jakoby, C F, Semenkovich
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Vascular Calcification in Dialysis Patients

Transplantation Proceedings, 2005
The risk factors for vascular calcification (VC) in dialysis patients include duration of dialysis, diabetes mellitus, aging, hyperphosphatemia, hyperparathyroidism, and calcium or vitamin D supplementation. This study was performed to evaluate the prevalence of and risk factors for VC in our dialysis population.One hundred twenty-nine chronic dialysis
H, Al Humoud   +7 more
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Vascular calcification

2015
Abstract Vascular calcification (VC) is a common feature of patients with advanced CKD and it could be, at least in part, the cause of increased cardiovascular mortality in these patients. From a morphologic point of view, there are at least two types of pathologic calcium phosphate deposition in the arterial wall—namely, intima ...
Adrian Covic   +3 more
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Vascular Calcifications

2018
Abstract Vascular calcifications lie within the artery wall, and appear to be linear, usually in association with blood vessels. The parallel or “tram-track” appearance of the calcifications in opposite walls of the artery is pathognomonic. They are more prevalent with age.
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Vascular Calcification: Key Roles of Phosphate and Pyrophosphate

International Journal of Molecular Sciences, 2021
Ricardo Villa-Bellosta   +1 more
exaly  

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