Results 341 to 350 of about 126,547 (360)
Some of the next articles are maybe not open access.
Vascular calcification in dermatopathology
The American Journal of Dermatopathology, 1979Calcification in cutaneous blood vessels is an uncommon finding in biopsies submitted for dermatopathological examination. Of 14 biopsy specimens showing the phenomenon that was studied by us, the greater number was from women who had a combination of severe diabetes, hypertension, and atherosclerosis.
Richard K. Winkelmann, Steven Kossard
openaire +3 more sources
The biology of vascular calcification
2020Vascular calcification (VC), characterized by different mineral deposits (i.e., carbonate apatite, whitlockite and hydroxyapatite) accumulating in blood vessels and valves, represents a relevant pathological process for the aging population and a life-threatening complication in acquired and in genetic diseases.
Quaglino D., Boraldi F., Lofaro F. D.
openaire +3 more sources
Pathophysiology of Vascular Calcification
Current Osteoporosis Reports, 2015Vascular calcification can lead to cardiovascular morbidity and mortality. The initiating factors and clinical consequences depend on the underlying disease state and location of the calcification. The pathogenesis of vascular calcification is complex and involves a transformation of vascular smooth muscle cells to an osteo/chondrocytic cell that ...
Neal X. Chen +2 more
openaire +2 more sources
Imaging for Vascular Calcification
Seminars in Dialysis, 2017AbstractChronic decline in renal function is accompanied by deterioration of bone structure and function and progressive calcification of the vascular system. Both disease states have been linked with increased morbidity and mortality in chronic kidney disease.
Paolo Raggi, W. Charles O'Neill
openaire +3 more sources
Inflammation and Vascular Calcification
Blood Purification, 2005Both vascular calcification and inflammation are common in patients with chronic kidney disease (CKD). In patients on dialysis, there is increased coronary artery and peripheral artery calcification compared to the general population. Both intimal (atherosclerotic) and medial calcification in CKD patients are associated with increased morbidity and ...
Neal X. Chen, Sharon M. Moe
openaire +3 more sources
Journal of Investigative Medicine, 2006
Recent evidence suggests that uremic vascular calcification is an active, cell-mediated process resembling osteogenesis in bone rather than passive precipitation. We identified increased expression of bone-associated proteins (osteopontin, bone sialoprotein, alkaline phosphatase, type I collagen) and the bone-specific transcription factor core-binding
Sharon M. Moe, Neal X. Chen
openaire +3 more sources
Recent evidence suggests that uremic vascular calcification is an active, cell-mediated process resembling osteogenesis in bone rather than passive precipitation. We identified increased expression of bone-associated proteins (osteopontin, bone sialoprotein, alkaline phosphatase, type I collagen) and the bone-specific transcription factor core-binding
Sharon M. Moe, Neal X. Chen
openaire +3 more sources
Current Opinion in Nephrology & Hypertension, 2005
Accumulating evidence suggests that the high cardiovascular mortality observed in patients with end-stage renal disease is due in part to the deleterious effects of vascular calcification that develops over time on dialysis. This review focuses on recent cell biological and animal studies that have shed light on the mechanisms and regulators of ...
openaire +2 more sources
Accumulating evidence suggests that the high cardiovascular mortality observed in patients with end-stage renal disease is due in part to the deleterious effects of vascular calcification that develops over time on dialysis. This review focuses on recent cell biological and animal studies that have shed light on the mechanisms and regulators of ...
openaire +2 more sources
Warfarin and Vascular Calcification
The American Journal of Medicine, 2016The vitamin K antagonist, warfarin, is the most commonly prescribed oral anticoagulant. Use of warfarin is associated with an increase in systemic calcification, including in the coronary and peripheral vasculature. This increase in vascular calcification is due to inhibition of the enzyme matrix gamma-carboxyglutamate Gla protein (MGP).
Timothy J. Poterucha +1 more
openaire +2 more sources
VASCULAR CALCIFICATION IN PATIENTS WITH KIDNEY DISEASE: The Vascular Biology of Calcification
Seminars in Dialysis, 2007AbstractVascular calcification is an active, cell‐mediated process that results from an imbalance between the promoters and inhibitors of mineralization. The process of vascular calcification shares many similarities with that of skeletal mineralization.
Rukshana Shroff, Catherine M. Shanahan
openaire +3 more sources
Omics research in vascular calcification
Clinica Chimica Acta, 2020Vascular calcification (VC), the pathological process of hydroxyapatite mineral deposition in the vascular system, is closely associated with aging, atherosclerotic plaque formation, cardiovascular disease (CVD) and diabetes mellitus (DM). Studies have shown that VC is related to cellular phenotypic changes, extracellular vesicles, disordered calcium ...
Meng Duan +5 more
openaire +4 more sources