Results 1 to 10 of about 621,125 (228)

Vascular cognitive impairment [PDF]

Dementia & Neuropsychologia, 2017
OBJECTIVE Vascular cognitive impairment is a major contributor to age-associated cognitive decline, both independently and as a contributor to mixed dementia syndromes.
Mônica Sanches Yassuda, Lea Tenenholz Grinberg   +1 more
doaj   +7 more sources

Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment

Acta Neuropathologica Communications, 2023
Vascular cognitive impairment (VCI) describes a wide spectrum of cognitive deficits related to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically involved in cognitive processes must feature as the main driver of VCI,
Acta Neuropathologica Communications, Vismitha Rajeev, Yuek Ling Chai, Luting Poh, Sharmelee Selvaraji, D. Fann, D. Jo, T. M. Silva, G. Drummond, C. Sobey, T. Arumugam, Christopher P. Chen, Mitchell Kim Peng Lai   +12 more
semanticscholar   +1 more source

Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia

Frontiers in Aging, 2021
Growing life expectancy will contribute to the on-going shift towards a world population increasingly comprised of elderly individuals. This demographic shift is associated with a rising prevalence of age-related diseases, among all age-related ...
Priya Balasubramanian, Jordan Delfavero, Adam Nyul-Toth, Adam Nyul-Toth, Amber Tarantini, Rafal Gulej, Stefano Tarantini, Stefano Tarantini, Stefano Tarantini   +8 more
doaj   +1 more source

Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment

Theranostics, 2022
The prevalence of cerebrovascular disease increases with age, placing the elderly at a greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a spectrum of cognitive deficits from mild cognitive impairment to dementia.
Vismitha Rajeev, D. Fann, Q. N. Dinh, Hyun Ah Kim, T. Michael, De Silva, Mitchell KP Lai, C. Chen, G. Drummond, C. Sobey, T. Arumugam   +10 more
semanticscholar   +1 more source

Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Scientific Reports, 2021
Sleep deprivation (SD) is a common condition and an important health concern. In addition to metabolic and cardiovascular risks, SD associates with decreases in cognitive performance.
Tamas Csipo, Agnes Lipecz, Cameron Owens, Peter Mukli, Jonathan W. Perry, Stefano Tarantini, Priya Balasubramanian, Ádám Nyúl-Tóth, Valeriya Yabluchanska, Farzaneh A. Sorond, J. Mikhail Kellawan, György Purebl, William E. Sonntag, Anna Csiszar, Zoltan Ungvari, Andriy Yabluchanskiy   +15 more
doaj   +1 more source

Neuroinflammation in Vascular Cognitive Impairment and Dementia: Current Evidence, Advances, and Prospects

International Journal of Molecular Sciences, 2022
Vascular cognitive impairment and dementia (VCID) is a major heterogeneous brain disease caused by multiple factors, and it is the second most common type of dementia in the world.
Zhengming Tian, X. Ji, Jia Liu
semanticscholar   +1 more source

The role of inflammasomes in vascular cognitive impairment

Molecular Neurodegeneration, 2022
There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical role in disease onset and progression.
Luting Poh, W. L. Sim, D. Jo, Q. N. Dinh, G. Drummond, C. Sobey, C. Chen, M. Lai, D. Fann, T. Arumugam   +9 more
semanticscholar   +1 more source

Hippocampal Vascular Supply and Its Role in Vascular Cognitive Impairment

Stroke, 2023
The incidence of age-related dementia is increasing as the world population ages and due to lack of effective treatments for dementia. Vascular contributions to cognitive impairment and dementia are increasing as the prevalence of pathologies associated ...
A. Johnson
semanticscholar   +1 more source

Placental growth factor as a sensitive biomarker for vascular cognitive impairment

Alzheimer's & Dementia, 2023
High‐performing biomarkers measuring the vascular contributions to cognitive impairment and dementia are lacking.
J. Hinman, F. Elahi, Davis Chong, H. Radabaugh, Adam R Ferguson, P. Maillard, Jeffrey F. Thompson, G. Rosenberg, A. Sagare, A. Moghekar, Hanzhang Lu, Tiffany Lee, Donna Wilcock, C. Satizabal, R. Tracy, S. Seshadri, K. Schwab, K. Helmer, Herpreet Singh, Pia Kivisäkk, S. Greenberg, C. DeCarli, J. Kramer   +22 more
semanticscholar   +1 more source

Lower cerebral blood flow predicts cognitive decline in patients with vascular cognitive impairment

Alzheimer's & Dementia, 2023
Chronic cerebral hypoperfusion is one of the assumed pathophysiological mechanisms underlying vascular cognitive impairment (VCI). We investigated the association between baseline cerebral blood flow (CBF) and cognitive decline after 2 years in patients ...
Maud van Dinther, A. Hooghiemstra, Esther E. Bron, A. Versteeg, A. Leeuwis, T. Kalay, Justine E. F. Moonen, Sanne Kuipers, W. Backes, J. Jansen, Mathias J P van Osch, G. Biessels, J. Staals, R. V. van Oostenbrugge   +13 more
semanticscholar   +1 more source