Results 11 to 20 of about 288,947 (195)

Vascular cognitive impairment [PDF]

open access: yesDementia & Neuropsychologia, 2017
Vascular cognitive impairment is a major contributor to age-associated cognitive decline, both independently and as a contributor to mixed dementia syndromes. This article reviews the current understanding of how vascular dysfunction contributes to cognitive impairment and dementia risk in older individuals and includes updated diagnostic criteria and ...
Mônica Sanches Yassuda   +1 more
doaj   +6 more sources

Vascular cognitive impairment [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 2004
Alzheimer first describe vascular dementia (VaD) 111 years ago. Despite this, its history has been dogged by misconceptions and it is only in the past decade that our understanding has matured. For the greater part of the 20th century dementia was routinely attributed to arteriosclerosis and consequent chronic cerebral ischaemia.
Vladimir Hachinski, Costantino Iadecola
  +8 more sources

Biological Risk Factors Influencing Vascular Cognitive Impairments: A Review of the Evidence

open access: yesBrain Sciences, 2023
Vascular cognitive impairment encompasses several types of deficits, ranging from mild cognitive impairment to dementia. Cognitive reserve refers to the brain’s ability to balance damage and improve performance through certain types of brain networks ...
Silvina Iluț   +6 more
doaj   +1 more source

Hemostasis biomarkers and incident cognitive impairment: the REGARDS study [PDF]

open access: yes, 2018
Essentials Cognitive disorders are increasing and vascular risk factors play a role in this. We performed a nested case control study of hemostasis biomarkers and cognitive impairment (CI). Higher baseline fibrinogen, factor VIII and D-dimer were related
Callas, P.W.   +7 more
core   +1 more source

Alois Alzheimer and vascular brain disease: Arteriosclerotic atrophy of the brain. [PDF]

open access: yes, 2015
Alois Alzheimer is best known for his description of neurofibrillary changes in brain neurons of a demented patient, identifying a novel disease, soon named after him by Kraepelin.
Engelhardt, Eliasz, Grinberg, Lea T
core   +2 more sources

Isolated Subtle Neurological Abnormalities in Mild Cognitive Impairment Types [PDF]

open access: yes, 2020
Background: Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects.
Azzarello, Delia   +7 more
core   +1 more source

Alzheimer and vascular brain diseases: Focal and diffuse subforms. [PDF]

open access: yes, 2015
Alois Alzheimer is best known for his description of the pre-senile neurodegenerative disease named after him. However, his previous interest in vascular brain diseases, underlying cognitive and behavioral changes, was very strong. Besides describing the
Engelhardt, Eliasz, Grinberg, Lea T
core   +2 more sources

Advances in Vascular Cognitive Impairment [PDF]

open access: yesStroke, 2013
Vascular cognitive impairment (VCI) has continued to evolve over the past year. Much of the data has been confirmatory with further work on risk factors, silent strokes, leukoaraiosis and lesion volume and location. The importance of the interaction between cerebrovascular disease and other causes of cognitive impairment, most importantly Alzheimer ...
Gorelick, Philip B, PANTONI, LEONARDO
openaire   +4 more sources

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

open access: yesRedox Biology, 2019
Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function.
Stefano Tarantini   +14 more
doaj   +1 more source

Longitudinal effects of metabolic syndrome on Alzheimer and vascular related brain pathology. [PDF]

open access: yes, 2014
Background/aimsThis study examines the longitudinal effect of metabolic syndrome (MetS) on brain-aging indices among cognitively normal (CN) and amnestic mild cognitive impairment (aMCI) groups [single-domain aMCI (saMCI) and multiple-domain aMCI (maMCI)]
Alzheimer's Disease Neuroimaging Initiative   +7 more
core   +4 more sources

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