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Vascular cognitive impairment [PDF]
Vascular cognitive impairment is a major contributor to age-associated cognitive decline, both independently and as a contributor to mixed dementia syndromes. This article reviews the current understanding of how vascular dysfunction contributes to cognitive impairment and dementia risk in older individuals and includes updated diagnostic criteria and ...
Mônica Sanches Yassuda +1 more
doaj +6 more sources
Vascular cognitive impairment [PDF]
Alzheimer first describe vascular dementia (VaD) 111 years ago. Despite this, its history has been dogged by misconceptions and it is only in the past decade that our understanding has matured. For the greater part of the 20th century dementia was routinely attributed to arteriosclerosis and consequent chronic cerebral ischaemia.
Vladimir Hachinski, Costantino Iadecola
+8 more sources
Biological Risk Factors Influencing Vascular Cognitive Impairments: A Review of the Evidence
Vascular cognitive impairment encompasses several types of deficits, ranging from mild cognitive impairment to dementia. Cognitive reserve refers to the brain’s ability to balance damage and improve performance through certain types of brain networks ...
Silvina Iluț +6 more
doaj +1 more source
Hemostasis biomarkers and incident cognitive impairment: the REGARDS study [PDF]
Essentials Cognitive disorders are increasing and vascular risk factors play a role in this. We performed a nested case control study of hemostasis biomarkers and cognitive impairment (CI). Higher baseline fibrinogen, factor VIII and D-dimer were related
Callas, P.W. +7 more
core +1 more source
Alois Alzheimer and vascular brain disease: Arteriosclerotic atrophy of the brain. [PDF]
Alois Alzheimer is best known for his description of neurofibrillary changes in brain neurons of a demented patient, identifying a novel disease, soon named after him by Kraepelin.
Engelhardt, Eliasz, Grinberg, Lea T
core +2 more sources
Isolated Subtle Neurological Abnormalities in Mild Cognitive Impairment Types [PDF]
Background: Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects.
Azzarello, Delia +7 more
core +1 more source
Alzheimer and vascular brain diseases: Focal and diffuse subforms. [PDF]
Alois Alzheimer is best known for his description of the pre-senile neurodegenerative disease named after him. However, his previous interest in vascular brain diseases, underlying cognitive and behavioral changes, was very strong. Besides describing the
Engelhardt, Eliasz, Grinberg, Lea T
core +2 more sources
Advances in Vascular Cognitive Impairment [PDF]
Vascular cognitive impairment (VCI) has continued to evolve over the past year. Much of the data has been confirmatory with further work on risk factors, silent strokes, leukoaraiosis and lesion volume and location. The importance of the interaction between cerebrovascular disease and other causes of cognitive impairment, most importantly Alzheimer ...
Gorelick, Philip B, PANTONI, LEONARDO
openaire +4 more sources
Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function.
Stefano Tarantini +14 more
doaj +1 more source
Longitudinal effects of metabolic syndrome on Alzheimer and vascular related brain pathology. [PDF]
Background/aimsThis study examines the longitudinal effect of metabolic syndrome (MetS) on brain-aging indices among cognitively normal (CN) and amnestic mild cognitive impairment (aMCI) groups [single-domain aMCI (saMCI) and multiple-domain aMCI (maMCI)]
Alzheimer's Disease Neuroimaging Initiative +7 more
core +4 more sources

