Results 81 to 90 of about 10,950,819 (369)

Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease

Movement Disorders, 2016
The purpose of this study was to examine the relationship between vascular disease (and vascular risk factors), cognition and motor phenotype in Parkinson's disease (PD).
N. Malek, M. Lawton, D. Swallow, K. Grosset, S. Marrinan, N. Bajaj, R. Barker, D. Burn, J. Hardy, H. Morris, N. Williams, N. Wood, Y. Ben-Shlomo, D. Grosset   +13 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Low-intensity pulsed ultrasound triggers a beneficial neuromodulation in dementia mice with chronic cerebral hypoperfusion via activation of hippocampal Fndc5/irisin signaling

Journal of Translational Medicine, 2023
Background Exercise-related signaling Fndc5/irisin expresses in brain and acts as a crucial regulator of cognitive function, but its detailed roles in vascular dementia (VaD) are still unclear.
Degang Song, Xiaomin Chen, Na Zhou, Yi Yuan, Shuo Geng, Cong Zhang, Zhe Zhao, Xingran Wang, Xinran Bao, Xifa Lan, Xiangjian Zhang   +10 more
doaj   +1 more source

ACC/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography

Circulation, 2006
Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic) A Collaborative Report from the American Association for Vascular Surgery/Society for Vascular Surgery,* Society for Cardiovascular Angiography and ...
A. Hirsch, Z. Haskal, N. Hertzer, C. Bakal, M. Creager, J. Halperin, L. Hiratzka, William R.C. Murphy, J. Olin, J. Puschett, K. Rosenfield, D. Sacks, J. Stanley, L. Taylor, C. White, John V. White, Rodney A. White, E. Antman, Sidney C. Smith, C. Adams, Jeffrey L. Anderson, D. Faxon, V. Fuster, R. Gibbons, S. Hunt, A. Jacobs, Rick A. Nishimura, J. Ornato, R. Page, B. Riegel   +29 more
semanticscholar   +1 more source

Embolotherapy in vascular disease [PDF]

American Journal of Roentgenology, 1984
Embolotherapy for nonneoplastic vascular diseases including hemorrhage and congenital vascular malformations is reviewed. Application of short, intermediate, and long-acting embolic materials to these conditions is presented along with potential complications associated with their misuse.
openaire   +3 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Statistical and Topological Summaries Aid Disease Detection for Segmented Retinal Vascular Images [PDF]

arXiv, 2022
Disease complications can alter vascular network morphology and disrupt tissue functioning. Diabetic retinopathy, for example, is a complication of types 1 and 2 diabetes mellitus that can cause blindness. Microvascular diseases are assessed by visual inspection of retinal images, but this can be challenging when diseases exhibit silent symptoms or ...
arxiv  

DNA Damage and Repair in Vascular Disease.

Annual Review of Physiology, 2016
DNA damage affecting both genomic and mitochondrial DNA is present in a variety of both inherited and acquired vascular diseases. Multiple cell types show persistent DNA damage and a range of lesions. In turn, DNA damage activates a variety of DNA repair
A. Uryga, K. Gray, M. Bennett
semanticscholar   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Exploring the underlying mechanisms of fisetin in the treatment of hepatic insulin resistance via network pharmacology and in vitro validation

Nutrition & Metabolism, 2023
Objective To characterize potential mechanisms of fisetin on hepatic insulin resistance (IR) using network pharmacology and in vitro validation. Methods Putative targets of fisetin were retrieved from the Traditional Chinese Medicine Systems Pharmacology
Tian Li, Junjun Ling, Xingrong Du, Siyu Zhang, Yan Yang, Liang Zhang   +5 more
doaj   +1 more source