Results 91 to 100 of about 11,304,059 (387)

Coronary intervention in anomalous origin of the right coronary artery (ARCA) from the left sinus of valsalva (LSOV): A single center experience

Indian Heart Journal, 2014
Objective: To assess the technical challenges in percutaneous coronary intervention of Anomalous right coronary artery arising from the left sinus of valsalva.
Kalaichelvan Uthayakumaran, Vijayakumar Subban, Anitha Lakshmanan, Balaji Pakshirajan, Ramkumar Solirajaram, Jaishankar Krishnamoorthy, Ezhilan Janakiraman, Ulhas M. Pandurangi, Latchumanadhas Kalidoss, Mullasari Ajit Sankaradas   +9 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Oxidative stress and vascular remodelling [PDF]

, 2005
Oxidative stress plays an important role in the pathophysiology of vascular diseases. Reactive oxygen species, especially superoxide anion and hydrogen peroxide, are important signalling molecules in cardiovascular cells. Enhanced superoxide production
Ana Fortuño, Beckman, Brandes, Cai, Cai, Cathcart, Cross, De Keulenaer, Dröge, Fortuño, Galis, Gorka San José, Griendling, Griendling, Griendling, Guillermo Zalba, Irani, Javier Díez, Kojda, Kristal, Lassegue, Li, Liu, Madamanchi, María U. Moreno, Moreno, Mueller, Pu, Rajagopalan, San José, Taniyama, Touyz, Touyz, Touyz, Ungvari, Ushio-Fukai, Virdis, Wainwright, Wang, Weber, Zafari, Zalba, Zalba, Zalba, Zalba   +44 more
core   +1 more source

Epigenetics and vascular diseases

Journal of Molecular and Cellular Cardiology, 2019
Cardiovascular disease remains the number one cause of death and disability worldwide despite significant improvements in diagnosis, prevention, and early intervention efforts. There is an urgent need for improved understanding of cardiovascular processes responsible for disease development in order to develop more effective therapeutic strategies ...
Stratton M. S., Farina F. M., Elia L.
openaire   +3 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Outcome of primary PCI – An Indian tertiary care center experience

Indian Heart Journal, 2014
Objective: To assess the feasibility and outcomes of primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) in Indian Scenario.
Vijayakumar Subban, Anitha Lakshmanan, Suma M. Victor, Balaji Pakshirajan, Kalaichelvan Udayakumaran, Anand Gnanaraj, Ramkumar Solirajaram, Jaishankar Krishnamoorthy, Ezhilan Janakiraman, Ulhas M. Pandurangi, Latchumanadhas Kalidoss, Ajit Sankardas Mullasari   +11 more
doaj   +1 more source

Assessment of resting myocardial blood flow in regions of known transmural scar to confirm accuracy and precision of 3D cardiac positron emission tomography

EJNMMI Research, 2023
Background Composite invasive and non-invasive data consistently demonstrate that resting myocardial blood flow (rMBF) in regions of known transmural myocardial scar (TMS) converge on a value of ~ 0.30 mL/min/g or lower.
Robert M. Bober, Richard V. Milani, Sergey M. Kachur, Daniel P. Morin   +3 more
doaj   +1 more source

Vascular Diseases In Patients With Chronic Myeloproliferative Neoplasms – Impact Of Comorbidity

Clinical Epidemiology, 2019
Background Patients with chronic myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF), are at high risk of vascular complications.
H. Frederiksen, S. Szépligeti, M. Bak, W. Ghanima, H. Hasselbalch, C. Christiansen   +5 more
semanticscholar   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Optical Coherence Tomography Angiography of the Optic Disc; an Overview. [PDF]

, 2017
Different diseases of the optic disc may be caused by or lead to abnormal vasculature at the optic nerve head. Optical coherence tomography angiography (OCTA) is a novel technology that provides high resolution mapping of the retinal and optic disc ...
Akil, Handan, Falavarjani, Khalil Ghasemi, Sadda, Srinivas R, Sadun, Alfredo A   +3 more
core   +3 more sources