Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis +19 more
wiley +1 more source
A Direct Relationship Between 'Blood Stasis' and Fibrinaloid Microclots in Chronic, Inflammatory, and Vascular Diseases, and Some Traditional Natural Products Approaches to Treatment. [PDF]
Kell DB, Pretorius E, Zhao H.
europepmc +1 more source
Comparison of therapeutic and diagnostic applications of a surface‐emitting light source with multiwavelength emission characteristics. Abstract Conventional light‐emitting‐diode‐based light sources suffer from rigidity, localized heating, and poor adaptability to skin deformation, limiting their use in skin‐attached medical devices.
In Ho Kim +10 more
wiley +1 more source
Pooled Multicenter Safety Analysis of Lupin's Intravitreal Biosimilar Ranibizumab (Ranieyes) in Chorioretinal Vascular Diseases. [PDF]
Chakraborty D +9 more
europepmc +1 more source
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim +16 more
wiley +1 more source
LRP1 Repression by SNAIL Results in ECM Remodeling in Genetic Risk for Vascular Diseases. [PDF]
Liu L +6 more
europepmc +1 more source
Bioactive glass (BAG) S53P4 is a synthetic bone substitute. Clinically it has been used in the treatment of benign bone tumor surgery, in spine surgery, in trauma surgery, in frontal sinus surgery, in diabetic foot osteomyelitis surgery, in mastoid surgery, in oral and maxillofacial surgery in more than 4000 patients, with excellent clinical long‐term ...
Sebastian CE Lindfors +2 more
wiley +1 more source
The Genus <i>Cordyceps</i> Sensu Lato: Their Chemical Constituents, Biological Activities, and Therapeutic Effects on Air Pollutants Related to Lung and Vascular Diseases. [PDF]
Park HJ.
europepmc +1 more source
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger +7 more
wiley +1 more source
Implantable Biosensors for Vascular Diseases: Directions for the Next Generation of Active Diagnostic and Therapeutic Medical Device Technologies. [PDF]
Alyami AM +3 more
europepmc +1 more source

