Results 31 to 40 of about 11,304,059 (387)

Development and validation of a prediction model to estimate risk of acute pulmonary embolism in deep vein thrombosis patients

open access: yesScientific Reports, 2022
Venous thromboembolism (VTE), clinically presenting as deep vein thrombosis (DVT) or pulmonary embolism (PE). Not all DVT patients carry the same risk of developing acute pulmonary embolism (APE).
You Li   +9 more
doaj   +1 more source

The Tie2 signaling pathway in retinal vascular diseases: a novel therapeutic target in the eye

open access: yesInternational Journal of Retina and Vitreous, 2020
Background Retinal vascular diseases such as neovascular age-related macular degeneration, diabetic retinopathy and/or diabetic macular edema, and retinal vein occlusion with macular edema—share several key pathophysiologic aspects including ...
Q. Nguyen   +6 more
semanticscholar   +1 more source

FAK Family Kinases in Vascular Diseases

open access: yesInternational Journal of Molecular Sciences, 2020
In various vascular diseases, extracellular matrix (ECM) and integrin expression are frequently altered, leading to focal adhesion kinase (FAK) or proline-rich tyrosine kinase 2 (Pyk2) activation.
James M. Murphy, Kyuho Jeong, S. Lim
semanticscholar   +1 more source

Endothelial to Mesenchymal Transition in Pulmonary Vascular Diseases

open access: yesBiomedicines, 2020
Lung diseases, such as pulmonary hypertension and pulmonary fibrosis, are life-threatening diseases and have common features of vascular remodeling. During progression, extracellular matrix protein deposition and dysregulation of proteolytic enzymes ...
E. Yun   +6 more
semanticscholar   +1 more source

Oral contraception and eye disease: findings in two large cohort studies [PDF]

open access: yes, 1997
AIM : To investigate the relation between oral contraceptive use and certain eye diseases. \ud \ud METHODS : Abstraction of the relevant data from the two large British cohort studies of the effects of oral contraception, the Royal College of General ...
Chappell, D.   +5 more
core   +2 more sources

Risk scoring system to predict contrast induced nephropathy following percutaneous coronary intervention

open access: yesIndian Heart Journal, 2014
Background: Contrast induced nephropathy (CIN) is associated with significant morbidity and mortality after percutaneous coronary intervention (PCI).
Suma M. Victor   +9 more
doaj   +1 more source

Mechanisms of vascular smooth muscle contraction and the basis for pharmacologic treatment of smooth muscle disorders [PDF]

open access: yes, 2016
The smooth muscle cell directly drives the contraction of the vascular wall and hence regulates the size of the blood vessel lumen. We review here the current understanding of the molecular mechanisms by which agonists, therapeutics, and diseases ...
Aggarwal, M.   +5 more
core   +1 more source

Vascular smooth muscle contraction in hypertension [PDF]

open access: yes, 2018
Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia and chronic kidney disease.
Alves-Lopes, Rheure   +6 more
core   +1 more source

The controversy on chronic cerebrospinal venous insufficiency

open access: yesVeins and Lymphatics, 2013
The objective of this review is to analyze the actual scientific controversy on chronic cerebrospinal venous insufficiency (CCSVI) and its association with both neurodegenerative disorders and multiple sclerosis (MS).
Paolo Zamboni   +3 more
doaj   +1 more source

MicroRNA regulation of endothelial homeostasis and commitment—implications for vascular regeneration strategies using stem cell therapies [PDF]

open access: yes, 2013
Human embryonic (hESC) and induced pluripotent (hiPSC) stem cells have broad therapeutic potential in the treatment of a range of diseases, including those of the vascular system.
Andrew H. Baker   +104 more
core   +1 more source

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