Results 261 to 270 of about 27,631,015 (306)

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Vascular plasticity in the gastric cancer environment: mechanisms, prognostic significance, and concepts of therapeutic interventions. [PDF]

Cancer Metastasis Rev
Chmiela M, Jaroniek P, Manzaneque JCR, Balcerczak E, Brzeziński M, Jeleń A, Mani S, Wosiak A, Gonciarz W.   +8 more
europepmc   +1 more source

Causal association between plasma vascular endothelial growth factor family proteins and placenta previa: A 2-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Hong Z, Xu Z, Huang Z, Li W, Liu Q.
europepmc   +1 more source

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Vascular Endothelial Growth Factor-C A Growth Factor for Lymphatic and Blood Vascular Endothelial Cells

Trends in Cardiovascular Medicine, 1998
The endothelial cells lining all vessels of the circulatory system have been recognized as key players in a variety of physiological and pathological settings. They act as regulators of vascular tone via the inducible nitric oxide system and in angiogenesis, the formation of blood vessels de novo. Aberrant regulation of endothelial cells contributes to
B, Enholm, L, Jussila, M, Karkkainen, K, Alitalo   +3 more
openaire   +2 more sources

The Expression of Vascular Endothelial Growth Factor C in Transplanted Corneas

Current Eye Research, 2009
To discuss the expression of vascular endothelial growth factor C (VEGF-C) after keratoplasty in rats.The Fischer 344 rat corneas were transplanted into Lewis rat eyes. The expression of VEGF-C in cornea was examined by immunohistochemistry and real-time PCR.
Shiqi, Ling, Chaoxiu, Qi, Wei, Li, Jiangang, Xu, Wenghui, Kuang   +4 more
openaire   +2 more sources

Developmental expression of vascular endothelial growth factor receptor 3 and vascular endothelial growth factor C in forebrain

Neuroscience, 2015
Increased understanding of the neurovascular niche suggests that development of the central nervous system (CNS) and its vasculature is coordinated through shared regulatory factors. These include the vascular endothelial growth factor (VEGF) family, reported to promote neuroproliferation and neuroprotection in addition to angiogenesis via its ...
M C, Ward, A M, Cunningham
openaire   +2 more sources